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Effect of sample size and P value filtering techniques on the detection of transcriptional changes induced in rat neuroblastoma (NG108) cells by mefloquine

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Academic year: 2020

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Figure 1Dose response curves for mefloquine against rat neuroblastoma (NG108) and primary embryonic rat neuronal cells.
Table 1: Gene specific primers, cycles, product sizes and annealing temperatures.
Figure 2Semi-quantitative RT-PCR of tubulin, pJunB, EST cJun (AI175959), IkappaB and GADD153 mRNA from DMSO or mefloquine-treated NG108 rat neuronal cell cultures
Figure 3P-Values (paired, two sided t-test, df = 7) for RT-PCR and microarray expression data (DMSO v mefloquine-treated NG108 cells) are highly correlated (r = 0.97, P < 0.002).
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