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Bovine Leukemia Virus Structural Gene Vectors Are Immunogenic and Lack Pathogenicity in a Rabbit Model

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Figure

FIG. 1. Genomic structures of BLV and BLV SGV with cisand U5 regions separated by white lines; labeled rectangles, open reading frames; asterisk, major BLV splice donor.Tax-responsive element; att, provirus integration sequence; E, viral RNA encapsidation
TABLE 1. BLV sequences in rabbit PBMCs by PCR andSouthern blot hybridization
FIG. 3. Semiquantitative PCR analysis to evaluate differences in proviral load. (A) PCR to detect BLV pol*, not determined (ND) because sample was not available; †, not determined because the animal died before harvest
TABLE 2. Levels of BLV Gag and Env antisera in treated rabbits

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