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Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

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Figure

Fig 1. Normal weight-gain of beta2-integrin knock-in mice on a high fat diet. (A) Weight gain by WT and KI mice on a HF diet
Fig 2. Reduced insulin sensitivity with increased glucose clearance by beta2-integrin knock-in mice fed a high fat diet
Fig 3. Increased neutrophil accumulation in adipose tissue of beta2-integrin knock-in mice, but normal macrophage infiltration and differentiation.(A-B) At the end of the 20-week HF-feeding study, WAT (A) and liver (B) from WT and KI mice were analyzed by
Fig 4. Elevated inflammation and elastase levels in skeletal muscle but not liver and WAT
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