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Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy

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Figure

Table 1 Clinical, pathological and molecular characterists of GISTs
Figure 1 Protein expression in GISTs from patients treated with imatinib mesylateextracts from three highly responsive GIST patients (lanes C-E) and from one poorly responsive patient with stable disease (lane B)
Table 2 List of proteins identified after OFFGEL and SDS-PAGE fractionation, tryptic digest, and MALDI-TOF MSanalysis
Figure 3 Immunohistochemistry of SCGF expression in GIST samples. A) Hematoxylin-eosin section of one representative slide from GIST 5.B) SCGF staining; strong SCGF positivity, consistent with western blotting, was restricted to the stroma compartment
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