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Selective assay for herpes simplex viruses expressing thymidine kinase.

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Figure

FIG.1.otrexateinwithfreevivalAfterculturesnumber 50-mm Effect of methotrexate and serum on sur- of 143 (TK-) cells
TABLE 2.populations Plaquing efficiencies ofmixed of TK+ and TK- viruses on 143 TK-cells in normal and methotrexate media
TABLE 3. Estimated frequencies of TK+ viruses in the progeny of viruses selected from plaques produced byB2006 in TK- cells under methotrexate TK+
FIG. 2. subclones Uptake of [3H]dThd by 14 of various viruses. cl-i

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