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Investigations of the mechanisms of receptor-mediated immunoglobulin transport in mammals and birds

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Academic year: 2019

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Figure

Figure 1.  Schematic representation of endosomal trafficking pathways in a polarized epithelia cell
Figure 2.  Immunoglobulin isotypes.  IgD and monomeric IgM are displayed on the surface of naïve B-cells
Figure 3. Schematic representation of FcRn function in the neonatal rodent gut.  IgG present in maternal milk passing through the acidic environment of the intestinal lumen is bound by FcRn at the apical surface of polarized intestinal epithelial cells
Figure 4.  Placental transfer of IgG in the gestating primate. FcRn present in placental syncitiotrophoblast cells binds to fluid-phase internalized IgG in acidic endosomes
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