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Aluminum Hydroxide Influences Not Only the Extent but Also the Fine Specificity and Functional Activity of Antibody Responses to Tick-Borne Encephalitis Virus in Mice

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Figure

FIG 1 Structure of flaviviruses and recombinant antigens used for serological analyses
FIG 2 Quality controls of antigens used in the study. (A) Coomassie-stained SDS-PAGE (5% phosphate gel) (44) and Western blotting (B) with a polyclonalmouse serum specific for C and E proteins (lanes 1, purified live virus; lanes 2, formalin-inactivated viru
FIG 3 TBE virion-specific antibody response after immunization without and with aluminum hydroxide (�Alu and �Alu, respectively)
FIG 5 (A) Ribbon diagram of DIII (side view) with amino acid positionsaffecting the binding of DIII-specific MAbs (B1 to B4) highlighted by coloredspheres: red, B1 and B4 (data)
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