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Molecular Basis of the Divergent Immunogenicity of Two Pediatric Tick-Borne Encephalitis Virus Vaccines

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Figure

FIG 2 Neutralizing antibody titers induced by two immunizations with (A) FSME-Immun Junior and (B) Encepur Children in participants aged 1 to 11 years.Data in each panel are individual neutralizing antibody titers, geometric mean titers (GMT) (wide horizon
TABLE 1 Rates of seropositivity and GMTs induced against Nd and K23 vaccine strain viruses after two immunizations with FSME-Immun Junioror Encepur Children, stratified by age group
FIG 3 Effect of amino acid substitutions in the Neudörfl strain TBEV envelope protein on the ability of hybrid viruses to detect neutralizing antibodies inducedby Encepur Children and FSME-Immun Junior
FIG 4 Effect of amino acid substitutions in the K23 strain TBEV envelopeprotein on the ability of hybrid viruses to detect neutralizing antibodies in-duced by Encepur Children and FSME-Immun Junior
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