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A Nuclear Inhibitor of NF-κB Encoded by a Poxvirus

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Figure

FIG. 1. Transcription kinetics of ORFV002infection in OFTu cells in the presence (ofCells were infected with wild-type virus OV-IA82 (MOIharvested at various time points postinfection (p.i.), and transcriptionlevels ofgene control) were assessed by RT-PCR
FIG. 2. Subcellular localization of ORFV002. OFTu cells were infected with OV-IA82Rv002GFP virus (MOI � 1 or 5), fixed with 4%formaldehyde at various time points postinfection (2, 3, 12, and 24 h p.i.), stained with DAPI, and examined by confocal microscopy.
FIG. 3. Replication characteristics of ORFV002virus OV-IA82(OV-IA82), deletion mutant (OV-IA82IA82Rv002) viruses in primary OFTu cells (MOIgrowth curves of OV-IA82, OV-IA82ruses in primary OFTu cells (MOIcurves of OV-IA82 and OV-IA82(OKTs; MOI deletion mut
FIG. 4. Effect of ORFV002 on NF-�tion. (A) OFTu cells were infected with OV-IA82 or OV-IA82B-regulated gene transcrip-002
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