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Mengovirus-Induced Rearrangement of the Nuclear Pore Complex: Hijacking Cellular Phosphorylation Machinery

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FIG. 1. Localization of Nups in cells infected with mengovirus and poliovirus. HeLa-3E cells were infected with the viruses with an input MOI100 PFU/cell and fixed at indicated times
FIG. 2. Electron microscopy of nuclear pores in infected cells. HeLa-3E cells were infected with mengovirus and poliovirus and fixed at 4 h p.i.The upper rows in panels A and B correspond to cross-sectioned nuclear envelopes, the middle rows are tangentially cut nuclear envelopes in
FIG. 3. Nup62 is hyperphosphorylated in mengovirus-infected cells. (A) [32The cold probe was exposed to the label for 6 h in ice
FIG. 4. Effect of L protein mutations on Nup62 phosphorylation.(A) HeLa-3E cells were infected with wild-type (wt) and T47E men-
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