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Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4

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Academic year: 2019

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Figure

Figure 1. Tie2 expression on mouse peripheral blood neutrophils. (A) Ly6G positivity was used to gate on neutrophils using forward and side scatter and Tie2 expression demonstrated as a log shift in fluorescence (FL-2) compared to isotype control
Figure 2. Chemotactic response of mouse neutrophils to rhAng-1 (rhAng-1 (0.7 control (rat IgG1), anti-Tie2 (12 and analysed for statistical significance using two-way ANOVA followed by Bonferroni’s test for multiple comparisons
Figure 3. Neutrophil migration in response to MAT.Ang-1 used to stain and images were taken at in vivo
Figure 4. MAT.Ang-1 induced neutrophil migration after depletion of peritoneal macrophages

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