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DNA-mediated Charge Transport in a Biological Context: Cooperation among Metalloproteins to Find Lesions in the Genome

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Figure

Figure 1.1. DNA in cells is wrapped around a histone core. Photooxidation of a metal complex tethered to DNA generates oxidative damage (Gox) at distant guanine sites in the nucleosome core particle (pdb ID: 1aoi)
Figure 1.2. Multiple copies of mitochondrial DNA (black) are found in mitochondria (green) organelles within the cell
Table S4.  Primer sequences used for nth inactivation, cloning and mutagenesis.
Figure 2.1. A model for DNA-mediated CT in DNA repair. In this model, DNA repair proteins, containing [4Fe4S]2+ clusters, for example, EndoIII (green) and MutY (orange), bind DNA, activating them towards oxidation to the [4Fe4S]3+ state
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