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Human Papillomavirus Type 16 E1∧E4-Induced G2 Arrest Is Associated with Cytoplasmic Retention of Active Cdk1/Cyclin B1 Complexes

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Academic year: 2019

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FIG. 1. 16E1∧activity. Control GE4 expression does not inhibit Cdk1/cyclin B kinase/S-synchronized SiHa cells were either harvested
FIG. 2. 16E1∧post-block release. Cells were double stained forE4 associates with Cdk1/cyclin B1
FIG. 3. Cyclin B1 associated with 16E1∧cyclin B1 (green), and mitochondria (red). A DAPI nuclear stain wasincluded (white)
FIG. 5. 16E1∧sidase, 16E1indicates a cell with predominantly cytoplasmic cyclin B1, and the small white arrow indicates a cell in which some of the cyclin B1 has enteredthe nucleus
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