• No results found

Adaptation of a Genotype 3 Hepatitis E Virus to Efficient Growth in Cell Culture Depends on an Inserted Human Gene Segment Acquired by Recombination

N/A
N/A
Protected

Academic year: 2019

Share "Adaptation of a Genotype 3 Hepatitis E Virus to Efficient Growth in Cell Culture Depends on an Inserted Human Gene Segment Acquired by Recombination"

Copied!
11
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

FIG 1 Diagram of the HEV genome summarizing the location and size, inamino acids, of nonviral sequences inserted into the HVR region
TABLE 1 Comparison of HVR clones from each passage level
FIG 3 Reversion of aa 882, 904, and 965 in the X region reduces the level ofsuccessful transfection
FIG 4 Removal of S17 sequence from p6 eliminates the adaptive effect of mostpoint mutations
+5

References

Related documents

We examined the occurrence of specific mRNAs in lymphatic cells and tissues, we partially purified an endogenous protease with substrate specificity for basic RXK/RR motifs, and

Therefore, we conclude that the SV40 late promoter does, indeed, contain a functional TR/RXR binding site that enables hormonal regulation of expression of the late genes of SV40

In order to analyze the ability of the recombinant MVM/cat genome to replicate and to express the CAT gene, pMVM/p38cat was introduced by transfection as a circular plasmid into

The increased 9284 precipita- tion observed for the 298 R/G, 427 WYV, 427 W/S, 420 I/R, and 432 K/A mutants is not simply the result of global conformational changes in the

The DI RNA containing the insert was replicated and packaged in the presence of helper virus, and cells infected with these DI particles produced a subgenomic RNA of the size

liposome formulation also induced significant levels of protective immunity, although the immunity was less than that induced by herpes simplex virus infection.. Acylated

able to stimulate expression of the gB promoter in trans- fected Vero cells, indicating that at least part of the positive regulatory effect of ICP27 is independent of other

The next theorem gives a new enumerative result on permutations avoiding simulta- neously 12 patterns of length 5 in which the first and the last elements are larger than any