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Inhibition of basal like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

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Figure

Fig. 1 Characterization of TNBC subtype cell lines. a Lysates preparedfrom cells grown for 48 h in medium containing 10% FCS wereevaluated for EGFR, HER2, SphK1, E-cadherin, and vimentin expressionby western blot
Fig. 2 The effect of EGFR inhibitors and FTY720 on cell proliferation measured by IncuCyte real-time imaging
Fig. 4a, a significant effect of treatment on tumor growth
Fig. 4 The effect of gefitinib-FTY720 combination therapy on TNBCxenograft tumor growth in nude mice
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