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Sabin Vaccine Reversion in the Field: a Comprehensive Analysis of Sabin-Like Poliovirus Isolates in Nigeria

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Academic year: 2019

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Figure

FIG 1 Sample population age and vaccination exposure. (A) Reported num-ber of OPV doses versus age (in years) for each AFP case included in this study;red line, best fit of mean doses per year of 1.45
FIG 3 Fixed recombinant de novo alignment identities. The traces show thesimilarity to the reference sequence for the longest de novo contigs with thehighest coverage smoothed with a 200-base sliding window
FIG 4 Immunity model checking. The modeled infection history and the modeled mean OPV-induced humoral antibody titer for each AFP case versusdifferences in the VP1 sequence from that of the reference strain are shown
FIG 5 Exposure date estimation. The exposure date for each sample was estimated from the campaign calendar and the inferred molecular clock, as described
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