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Entry versus Blockade of Brain Infection following Oral or Intraperitoneal Scrapie Administration: Role of Prion Protein Expression in Peripheral Nerves and Spleen

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Academic year: 2019

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Figure

FIG. 1. HaPrP detection in various tissues of Tg7-HaPrP/MoPrP(�sciatic nerves (0.5 mg) were loaded per lane, and Western blots were developedas above
FIG. 2. (Top) Time from inoculation until severe clinical disease in NSE-HaPrP/MoPrP(�scrapie strain 263K by the i.c., oral, and i.p
FIG. 4. Effect of MoPrP expression [(�NSE-HaPrP/MoPrP(cumulative deaths due to scrapie
FIG. 5. Possible pathways of neuroinvasion after peripheral scrapie infection.Direct invasion of the CNS by nerves may occur after peripheral infection with

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