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Increase in the frequency of hepadnavirus DNA integrations by oxidative DNA damage and inhibition of DNA repair.

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Academic year: 2019

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Figure

FIG. 1. Flow diagrams of the single-cell cloning protocols for the H2O2 (A)and 3-AB (B) experiments with the LMH-D21-6 lineage, a subclone of LMH-D2
FIG. 3. DHBV DNA integration pattern in first-generation subclones de-rived from LMH-D21-6-19 and replicative forms from first-generation subclones.
TABLE 3. Summary of results of second-round subcloning andgrowth of subclones in regular cell culture medium (control),1.0 mM 3-ABA (specificity control), or 1.0 mM 3-AB
FIG. 5. DHBV DNA integration pattern in second-generation subclones de-rived from LMH-D21-6-19-15

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