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Systematic analysis of splice-site-creating mutations in cancer

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Figure

Figure 1. Splice-Site-Creating Mutation Discovery(A) Examples of splice-site-creating mutations for different conventionally annotated mutation types
Figure 2. Sequence Contexts and Characteristics of Splice-Site-Creating Mutations(A) Frequency distribution of splice-site-creating mutations relative to the newly created splice junction, with high frequency shown at the third nucleotide positionaway from
Figure 3. Junction Allele Fraction of Splice-Site-Creating Mutations(A) The junction allele fraction (JAF) is defined as the number of reads supporting the alternative spliced junction relative to total junction spanning reads
Figure 4. Splice-Site-Creating Mutations across Genes and Cancer Types(A) Distribution of splice-site-creating mutations in each gene separated by the total number of mutations in each gene.specific to LGG and BRCA, respectively.(C) Proteins Timeless (PAB d
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