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Modelling the cost-effectiveness of combination therapy for early, rapidly progressing rheumatoid arthritis by simulating the reversible and irreversible effects of the disease

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Figure

Figure 1Model schematic.ACR, American College ofRheumatology; DAS, DiseaseActivity Score; HAQ, HealthAssessment Questionnaire.
Figure 2Distribution of patients on each treatment3 subsequent lines switched to the therapy with the bestresponse
Figure 3Consequence oftreatments. Grey lines representpatients who started onmethotrexate (MTX)monotherapy
Table 1Clinical outcomes and costs over 30 years: alternative scenarios
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