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The crystal structure of the Hazara virus nucleocapsid protein

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Figure

Fig. 1 Amino acid sequence alignment of CCHFV N strains Baghdad-12, YL04057 and IbAr10200 with HAZV N strain JC280
Fig. 2 HAZV N purification by ion exchange chromatography. HAZV N was separated from GST-HAZV N and GST using ion exchange chromatography.a Protein elution was monitered with an A280 absorbance trace; protein that flowed through the column without binding
Fig. 3 Circular dichroism analysis of CCHFV N and HAZV N. Circular Dichroism was used to analyse the secondary structure of both HAZV andminima at 208 nm and 222 nm.CCHFV N proteins
Fig. 4 The crystal structure of the HAZV N monomer and alignment of the sequence of HAZV N with the secondary structural elements.domain, and helixthe position of the secondary structural elements in (green) is linked to C-terminus of the globular domain b
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