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Conservation of Nef function across highly diverse lineages of SIVsmm

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Figure

Figure 1Evolutionary relationships among HIV-2 and SIVsmm Nef sequencespresent study and the SIVmac239 Evolutionary relationships among HIV-2 and SIVsmm Nef sequences
Figure 3nef duced with HIV-1 NL4-3 constructs coexpressing the indicated CD3, CD28 and MHC-I
Figure 4Modulation of CXCR4 and the MHC-II associated invariant chainModulation of CXCR4 and the MHC-II associated invariant chain
Figure 6nef Jurkat cells stably transfected with an NFAT-dependent reporter gene following transduction with the indicated HIV-1 Nef/eGFP constructs and subsequent stimulation with PHA
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