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Proteolytic activation of tick-borne encephalitis virus by furin.

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Figure

FIG. 1. Inhibition of prM cleavage by dec-RVKR-CMK. Monolayers ofBHK-21 cells were treated with the inhibitor at the indicated concentrations and
FIG. 2. SDS-PAGE and immunoblot analysis of TBE virus grown in LoVoand BHK-21 cells. Cells were infected at an MOI of 10, and virus was harvested
FIG. 6. Fusion activity of in vitro-activated immature virions. Different virus preparations were tested for their ability to induce fusion of C6/36 mosquito cells atpH 5.5
FIG. 7. Oligomeric rearrangements of E protein in in vitro-activated immature virions

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