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Natural and artificial routes to pluripotency

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Figure

Fig. 1. ES cell pluripotency network. The subset of target genes for Oct4, Sox2 and Nanogwhereas hatched lines indicate that subgroups contain members that either up- or down-Solid lines indicate that all members within a subgroup regulate transcription in
Fig. 2. Epigenetic changes during natural reprogramming. Epigenetic profiles are represented qualitatively and were assembled from datapublished previously (Reik 2007; Chang et al., 2005; Zernicka-Goetz et al., 2009; Shi and Wu, 2009)
Fig. 3. blastocysts formation. Cell nuclei and oocyte pro-nuclei are drawn in solid brown
Fig. 4. Generation of induced pluripotent stem (iPS) cells by lentiviral introduction of

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