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<p>Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo</p>

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Figure 2 cell viability treated with complex of T9(dr) or TP and tested by MTT assay. (A) T9(dr) and (B) TP.Abbreviation: TP, transportan.
Figure 3 T9(dr) or TP transported sirna into (A) 293T and (B) a549 cell lines. after T9(dr) or TP and cy3-conjugated sigFP were incubated for 15 minutes, the complex was transfected into cells seeded in eight-well chamber. At 24 hours post-transfection, cells were fixed, mounted with DAPI, and observed under a microscope (20×).Abbreviation: TP, transportan.
Figure 5 T9(dr) delivered functional sirna into (A) MDcK and (B) A549 cell lines. MDCK and A549 cells were treated with siNP and infected with influenza virus of MOi =0.01
Figure 6 siNP transported by T9(dR) inhibited the replication of PR8 influenza virus in vivo. BALB/c mice were divided into seven groups, intravenously injected PBS, siGFP, siNP with T9(dR) or TP, and infected with influenza. Mouse weight was recorded (A)

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