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Epigenetic reprogramming of the genome from the germ line to the embryo and back again

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Figure

Fig. 1. Mammalian oocytes and early development. Monotreme oocytes contain largeamounts of yolk (telocithal), the marsupial eggs are less yolky, and yolk is largely absent ineutherian mammals
Fig. 2. Model for the role of the H19/Igf2 imprinting centre. The silencer element (redellipse) functions on the paternal chromosome to prevent transcriptional activation of H19.Hypermethylation at the DMD (small black circles) and other epigenetic modific
Fig. 3. Epigenetic modifications in the germ line. During the proliferation ofprimordial germ cells (PGC) and their entry into the gonads, extensive epigeneticmodifications occur
Fig. 4. Early events in preimplantation mouse development. Some of the earliest eventsin development, prior to the onset of S-phase, are shown in this schematic diagram

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