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ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

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Figure

Figure 1: Identification of an ERK1/2 phosphorylation site on TRF2. specific anti-pTRF2 antibody and detected by immunoblotting with an anti-TRF2 antibody (IP)
Figure 2: TRF2 is phosphorylated following physiological or pathological activation of ERK1/2
Figure 3: TRF2 and pERK1/2 interact in the cytoplasm of a melanoma cell line and human cancer samples
Figure 4: TRF2 half-life is dependent on TRF2 phosphorylation of S323 by ERK1/2. loading controls and expressed relative to the control conditions (results are expressed as mean ± SD)
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