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Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL

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Figure

Figure 1: Elektra mutation in Slfn2 prevents lymphoproliferative disease mediated by BCL2-transgene combined with FAS loss-of-function
Figure 2: Elektra mutation in Slfn2 inhibits development and progression of T-ALL induced by ICN1
Figure 3: Elektra/p53ERTAM mice have normal T-cell numbers but cells still lack the ability to proliferate
Figure 4: Down regulation of p53 partially restores development and progression of T-ALL in elektra mice
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