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Vaccine efficacy and T helper cell differentiation change with aging

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Figure

Figure 1: Lingering inflammatory cytokines and lung damage in aged lungs during influenza infection
Figure 2: Protection from influenza and secondary bacterial infection by NP vaccination
Figure 3: NP vaccination reduces lung inflammatory mediators and damage in influenza infected young but not aged mice
Figure 4: Impact of NP mAb transfer on influenza infection. Young (2-3 mos.) and aged (19-22 mos.) C57BL/6 mice were administered anti-NP mAb or isotype control mAb (350 ug i.p.) on days -1 and day 0
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