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Betaine Homocysteine Methyltransferase, Disease and Diet: The Use of Proton Nuclear Magnetic Resonance on Biological Methylamines

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Figure

Table of Abbreviations and Symbols
Figure 1.1 Total death rate and CVD-death rate for selected countries (1997-2001).
Figure 1.2 to S-adenosylmethionine (SAM) and then to S-adenosylhomocysteine (SAH). Homocysteine can also be broken down by cystathionine Homocysteine metabolism (abridged)
Figure 1.4 Oxidation of choline to produce methylene-tetrahydrofolate (THF). Choline is oxidised in CHCHtwo steps to glycine betaine (via betaine aldehyde)
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Outline

Thesis Aims Size Exclusion Chromatography Mass Spectrometry Analysis Genomic Sequencing of Rat BHMT Spin, and the Nuclear Magnetic Resonance Effect Quantitative NMR Spectroscopy Validation of 1 H-NMR Spectroscopy for Urine Methylamine Measurements Materials and Methods The Endpoint Assay Methyl Donors in BHMT

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