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Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H- ras

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Academic year: 2020

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Figure

Figure 1: Mutant H-ras-mediated cellular transformation stimulates eV-mediated emission of the H-ras oncogene and extracellular genomic dnA
Figure 2: cellular transformation overcomes resistance of immortalized epithelial cells and astrocytes to the uptake of H-ras-containing eVs
Figure 3: uptake of mutant H-ras-of RAS-3-derived EVs. After 36 days, the remaining foci were individually re-plated (dotted line), and the cells expanded and passaged 6 times (80–100 days), resulting in gradual disappearance of their foci-forming ability
Figure 4: uptake of mutant H-rassurvival, which is compromised under growth factor and nutrient starvation conditions (Starvation Media)
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