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Human telomerase reverse transcriptase and glucose regulated protein 78 increase the life span of articular chondrocytes and their repair potential

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Table 1 OA cartilage histopathology grade assessment; grading methodology
Figure 1 Effect of hTERT and GRP78 on the proliferation ofrabbit chondrocytes. Growth curves of cultures of nontransfectedcontrol chondrocytes from young and old rabbits (YRA and ORA,respectively) and hTERT (YRA + hTERT and ORA + hTERT) and GRP78(YRA + hTE
Figure 5 Macroscopic and immunostaining of regeneratedcartilage after implantation. Postoperative appearance of repairedosteochondral defects in old rabbits implanted with scaffoldsseeded with either nontransfected (top panels) or hTERT- andGRP78-transfect
Figure 6 Osteoarthritis score. The histopathology of the OAcartilage samples from all 4 groups (n = 24) were analyzedaccording to standard grading and staging of OA cartilagehistopathology

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