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The birth of a human specific neural gene by incomplete duplication and gene fusion

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Figure

Fig. 1 HYDIN duplication and evolution. a Comparison of human genomic sequence from the donor locus on chromosome 16q22.2 (top) to the acceptorlocus on chromosome 1q21.1 (middle) shows a 364 kbp duplication (blue lines) including exons 6-84 of the 86-exon
Fig. 2 HYDINof 153 MIPs were used for genotyping and events were detected by an automated caller
Fig. 3 (See legend on next page.)
Fig. 4 Tissue-specific expression ofwhile all isoforms of HYDIN/HYDIN2 isoforms. a RT-PCR analysis over a 15 bp deletion in exon 46 of HYDIN2 compares the relativeabundance of HYDIN (top band, 321 bp) and HYDIN2 (bottom band, 306 bp) mRNA in different adul
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