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A Cell Penetrating Peptide for Inhibiting MAPKAP Kinase 2 Mediated Inflammatory Cytokine Release Following Glial Cell Activation

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Figure

Figure 1. 1 week mixed cortical culture image under (a) 10× and (b) 40× objectives; immunostained for neurons (β-3-tub), astrocytes (GFAP), microglia (Iba1), and cell nuc-lei (Hoechst 33,342) within the same culture (overlay)
Figure 2. Mean IL-6 and IL-1β concentrations (in pg/mL) following 4, 8, and 24 hour treatments with TNF-α or TNF-α + MK2i
Figure 3. %Dead indicates the percentage of dead cells per well and illustrates differences in cell viability when cells are treated with TNF-α + MK2i vs
Figure 5. Mean ramification index (RI) for microglia following 24 hour treatments with TNF-α or TNF-α + MK2i
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