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miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells

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Figure

Figure 1: Relative expression of miR-27a in OS, healthy bones and different OS cell lines
Figure 3: Effects of miR-27a and miR-27a* inactivation on properties of LM7 cells. (A) GFP fluorescence and morphology of LM7-SIN-GFP, LM7-miR-27a-Sponge and LM7-miR-27a*-Sponge cells; images were obtained using 10x magnification
Figure 4: Effects of miR-27a* inactivation in HOS and KHOS cells. (A, B) In vitro invasion assay of HOS-SIN-GFP and HOS-miR-27a*-Sponge cells (A) and of KHOS-SIN-GFP and KHOS-miR-27a*-Sponge cells (B) Images were obtained using 10x magnification
Figure 5: CBFA2T3 is a target of miR-27a and miR-27a*. (A) A box plot of CBFA2T3 expression in OS and healthy bones (Normal) according to our published Affymetrix microarray data [19]
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