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Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models

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Academic year: 2020

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Figure

Figure 1: Anti-angiogenic activity of iVR1 in vivocompared to vehicle and CP; . (A) Chemical structure of iVR1 tetrameric tripeptide that has a calculated molecular mass of 2362.02 g/mol
Figure 2: iVR1 inhibited growth and neo-angiogenesis of syngenic and xenograft colorectal tumors
Figure 3: iVR1 inhibited the recruitment of monocyte-macrophages in syngenic and xenograft colorectal tumors
Figure 4: iVR1 inhibited the recruitment of smooth muscle cells in xenograft colorectal tumors blocking VEGFR1 activation
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