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Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma

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Figure

Figure 1: TLR2 is expressed on HNSCC cell lines and promotes growth of organoids in a 3D model of in vitrostaining (gray shaded histogram)
Figure 2: Human primary HNSCC tumors express TLR2, and stimulation of TLR2 with zymosan enhances growth of organoids in vitro
Figure 3: Zymosan activates MAPK/ERK and NF-κB signaling pathways in HNSCC, which can be blocked by anti-TLR2 antibody
Fig. 4C and 4D). Importantly, the single treatment with the

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