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Design, synthesis and biological activity of hydroxybenzoic acid ester conjugates of phenazine-1-carboxylic acid

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Figure

Fig. 1 The structures of PCA and its derivatives
Fig. 3 Synthetic route of target compounds. Reagents and conditions: hydroxybenzoic acid ester,  CHa oxalyl chloride,  CH2Cl2, DMF, reflux, 8 h; b alcohol, reflux, overnight; c 2Cl2, room temperature to reflux, 2 h
Table 1 Fungicidal activity of compounds 5a–5p against five plant fungi in vitro at 50 μg/mL (inhibition rate/%)
Fig. 5 The toxicity index of conjugates 5a–5p

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