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Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

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Academic year: 2020

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Figure

Figure 1 Study hypothesis. It was hypothesised that brain penetration in normal brain would increase with therapeutic serum concentrations oflapatinib due to the effect of lapatinib on drug efflux pumps
Table 1 Patient demographics and disease characteristicsof all patients recruited
Figure 2 Fully automated and good manufacturing process-compatible synthesis developed to label lapatinib with radiolabelled carbon-11 inthe benzylic position
Figure 3 (See legend on next page.)
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