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Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination.

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Figure 2. Increased RAG cutting on the acetylated nucleosome arrays. RAG cutting was performed on the acetylated (Acet) and non-acetylatedthat the PCR reactions were in the semi-quantitative range (for each set of RAG cut templates) was achieved by confirmi
Figure 4. Addition of purified remodelling complexes stimulates RAG cutting on acetylated arrays
Figure 6. Acetylation does not increase sliding on mono-nucleosomesby ACF or ISWI. Sliding assay using mono-nucleosomes reconstitutedwith acetylated and non-acetylated histones onto a 12-RSS fragmentfrom MAB5
Figure 7. Binding and remodelling by wild-type ACF and ACF bromodomain mutant complexes on acetylated and non-acetylated chromatin
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