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Chlorogenic Acid Attenuates High Mobility Group Box 1 (HMGB1) and Enhances Host Defense Mechanisms in Murine Sepsis

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Figure

Figure 1. The effect of chlorogenic acid on in vitro cytokine and chemokine release. Cytokine and chemokine release from macrophages were determined after 16 h of LPSstimulation in the presence or absence of various concentrations of chlorogenic acid(CA)
Figure 2. Chlorogenic acid protected against sepsis-induced mortality. Chlorogenic acid was administered at various doses after the in-duction of sepsis via an intraperitoneal injection of LPS or CLP
Figure 3. Chlorogenic acid protected against CLP-induced organ injury. Assessment of serum enzyme activities and histological analysis
Figure 4. The effects of chlorogenic acid on CLP-induced cytokine and chemokine release
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