REOVIRIDAE
REOVIRIDAE
ROTAVIRUS
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Los
Los
Rotavirus
Rotavirus
se transmiten por la ruta
se transmiten por la ruta
fecal oral, infectando células del
fecal oral, infectando células del
intestino delgado y produciendo una
intestino delgado y produciendo una
enterotoxina, provocando una
enterotoxina, provocando una
gastroenteritis que puede llevar a una
gastroenteritis que puede llevar a una
diarrea e incluso deshidratación.
diarrea e incluso deshidratación.
Aunque fueron descubiertos en 1973 y
Aunque fueron descubiertos en 1973 y
son responsables de más del 50% de
son responsables de más del 50% de
los ingresos hospitalarios de niños con
los ingresos hospitalarios de niños con
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Proteínas
Proteínas
•
•
El virión está formado por seis proteínas
El virión está formado por seis proteínas
(VP). Estas proteínas estructurales se
(VP). Estas proteínas estructurales se
llaman VP1, VP2, VP3, VP4, VP5 y
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Proteínas Estructurales
Proteínas Estructurales
La VP1 está situada en el núcleo del virus y es
La VP1 está situada en el núcleo del virus y es
una RNA polimerasa. En una célula infectada
una RNA polimerasa. En una célula infectada
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•
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Proteínas No Estructurales
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Serotipos Comunes en
Serotipos Comunes en
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