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A Bayesian mixture modelling approach for spatial proteomics.

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Figure

Fig 1. (a) PCA plot of the 1st and 2nd principal components for the curated marker proteins of the mouse stem cell data
Fig 2 (right) demonstrates a range of probabilistic assignments of proteins to organelles and sub-cellular niches
Fig 4 illustrates one example of the importance of capturing uncertainty. The E3 ubiquitin- ubiquitin-protein ligase TRIP12 (G5E870) is an integral part of ubiquitin fusion degradation pathway and is a protein of great interest in cancer because it regulat
Fig 4. Violin plot revealing the posterior distribution of localisation probabilities of protein E3 ubiquitin-protein ligase (G5E870) to organelles and sub-cellular niches
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