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One-Versus-All (OVA) comparisons list_1 AML with t(15;17) versus rest. Sequence. Number Probe Set ID Gene Symbol Title q-value t-test statistic

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One-Versus-All (OVA) comparisons list_1 AML with t(15;17) versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 209732_at CLECSF2

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily

member 2 (activation-induced) 4.12E-252 -48.36 BC005254.1 Hs.85201

2 204425_at ARHGAP4 Rho GTPase activating protein 4 8.98E-198 -43.44 NM_001666.1 Hs.3109

3 205771_s_at AKAP7 A kinase (PRKA) anchor protein 7 4.99E-120 -37.24 AL137063 Hs.12835

4 211990_at HLA-DPA1

major histocompatibility complex, class II,

DP alpha 1 2.75E-95 -36.88 M27487.1 Hs.914

5 226890_at KIAA1336 KIAA1336 protein 1.47E-138 -32.56 AW088668 Hs.145365

6 211991_s_at HLA-DPA1

major histocompatibility complex, class II,

DP alpha 1 8.47E-138 -30.95 M27487.1 Hs.914

7 225507_at DKFZp564B0769 SR rich protein 6.55E-128 -30.92 BF591408 Hs.18368

8 227353_at EVER2 epidermodysplasia verruciformis 2 2.53E-48 -29.21 BE671663 Hs.15284

9 229041_s_at

Homo sapiens, clone IMAGE:4766144,

mRNA 1.10E-128 -28.95 AW303397 Hs.72080

10 217478_s_at HLA-DMA

major histocompatibility complex, class II,

DM alpha 9.90E-93 -28.81 X76775 Hs.77522

11 224958_at KIAA1321 KIAA1321 protein 1.19E-123 -28.77 AI743689 Hs.24336

12 236322_at ESTs 6.49E-71 -28.72 AA830854 Hs.187810

13 232617_at CTSS cathepsin S 1.25E-96 -28.53 AK024855.1 Hs.181301

14 238949_at FLJ31951 hypothetical protein FLJ31951 4.43E-86 -28.02 BF681162 Hs.349306

15 228046_at LOC152485 hypothetical protein LOC152485 1.98E-115 -27.47 AA741243 Hs.351270

16 236554_x_at EVER2 epidermodysplasia verruciformis 2 4.73E-53 -27.38 AI370364 Hs.15284

17 204661_at CDW52 CDW52 antigen (CAMPATH-1 antigen) 1.48E-112 -26.71 NM_001803.1 Hs.276770

18 34210_at CDW52 CDW52 antigen (CAMPATH-1 antigen) 1.39E-111 -26.52 N90866 Hs.276770

19 209312_x_at HLA-DRB1

major histocompatibility complex, class II,

DR beta 1 2.68E-62 -26.50 U65585.1 Hs.375570

20 208306_x_at HLA-DRB4

major histocompatibility complex, class II,

DR beta 4 3.09E-68 -26.46 NM_021983.2 Hs.318720

21 207697_x_at LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains),

member 2 1.26E-105 -26.39 NM_005874.1 Hs.22405

(2)

23 204362_at SCAP2 src family associated phosphoprotein 2 1.13E-57 -25.50 NM_003930.1 Hs.52644

24 212998_x_at HLA-DQB1

major histocompatibility complex, class II,

DQ beta 1 1.93E-103 -25.11 AI583173 Hs.73931

25 226764_at LOC152485 hypothetical protein LOC152485 5.01E-102 -24.86 BG542955 Hs.351270

26 210146_x_at LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains),

member 2 3.66E-102 -24.85 AF004231.1 Hs.22405

27 214651_s_at HOXA9 homeo box A9 1.93E-100 -24.70 U41813.1 Hs.127428

28 213537_at HLA-DPA1

major histocompatibility complex, class II,

DP alpha 1 2.60E-100 -24.56 AI128225 Hs.914

29 227598_at LOC113763 hypothetical protein BC011406 3.31E-50 -24.46 AI762857 Hs.123177

30 204670_x_at HLA-DRB5

major histocompatibility complex, class II,

DR beta 5 1.85E-47 -24.40 NM_002125.1 Hs.352392

31 204057_at ICSBP1

interferon consensus sequence binding

protein 1 8.79E-99 -24.37 AI073984 Hs.14453

32 226077_at FLJ31951 hypothetical protein FLJ31951 1.27E-50 -24.27 AL553942 Hs.349306

33 209619_at CD74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II

antigen-associated) 9.76E-41 -24.23 K01144.1 Hs.84298

34 229040_at

Homo sapiens, clone IMAGE:4766144,

mRNA 1.35E-97 -24.12 AW303397 Hs.72080

35 219593_at PHT2 peptide transporter 3 6.60E-97 -24.07 NM_016582.1 Hs.237856

36 243618_s_at LOC152485 hypothetical protein LOC152485 4.14E-95 -23.94 BF678830 Hs.351270

37 216899_s_at SCAP2 src family associated phosphoprotein 2 2.76E-60 -23.92 AC003999 Hs.52644

38 223280_x_at MS4A6A

membrane-spanning 4-domains,

subfamily A, member 6A 1.36E-93 -23.79 AF253977.1 Hs.17914

39 225639_at SCAP2 src family associated phosphoprotein 2 6.94E-49 -23.65 N21390 Hs.52644

40 228113_at STAT3

signal transducer and activator of transcription 3 (acute-phase response

factor) 5.19E-45 -23.47 R62453 Hs.321677

41 213002_at MARCKS

myristoylated alanine-rich protein kinase

C substrate 2.92E-80 -23.43 BF347326 Hs.75607

42 203948_s_at MPO myeloperoxidase 1.94E-28 23.43 J02694.1 Hs.1817

43 204319_s_at RGS10 regulator of G-protein signalling 10 1.38E-66 -23.39 NM_002925.2 Hs.82280

(3)

45 221203_s_at FLJ10201 hypothetical protein FLJ10201 7.07E-70 -23.33 NM_018023.2 Hs.318127

46 225099_at LOC200933 hypothetical protein LOC200933 6.70E-92 -23.32 AK025697.1 Hs.6994

47 205453_at HOXB2 homeo box B2 1.04E-87 -23.32 NM_002145.1 Hs.2733

48 204174_at ALOX5AP

arachidonate 5-lipoxygenase-activating

protein 7.84E-80 -23.31 NM_001629.1 Hs.100194

49 221087_s_at APOL3 apolipoprotein L, 3 6.15E-46 -23.29 NM_014349.1 Hs.241535

50 219105_x_at ORC6L

origin recognition complex, subunit 6

homolog-like (yeast) 5.49E-61 -23.26 NM_014321.1 Hs.49760

51 204160_s_at ENPP4

ectonucleotide

pyrophosphatase/phosphodiesterase 4

(putative function) 3.05E-88 -23.20 AW194947 Hs.54037

52 224356_x_at MS4A6A

membrane-spanning 4-domains,

subfamily A, member 6A 6.33E-90 -23.13 AF237908.1 Hs.17914

53 205767_at EREG epiregulin 3.33E-91 -23.11 NM_001432.1 Hs.115263

54 235753_at

Homo sapiens cDNA FLJ34835 fis, clone

NT2NE2010150. 1.26E-90 -23.03 AI492051 Hs.196169

55 205863_at S100A12

S100 calcium binding protein A12

(calgranulin C) 3.17E-87 -22.96 NM_005621.1 Hs.19413

56 38487_at STAB1 stabilin 1 3.93E-24 22.91 D87433 Hs.301989

57 226878_at

Homo sapiens mRNA full length insert

cDNA clone EUROIMAGE 1964662 3.26E-82 -22.90 AL581873 Hs.11135

58 212252_at CAMKK2

calcium/calmodulin-dependent protein

kinase kinase 2, beta 1.71E-54 -22.86 AA181179 Hs.108708

59 208594_x_at ILT8

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains),

member 6 2.53E-69 -22.83 NM_024318.1 Hs.306230

60 212873_at HA-1 minor histocompatibility antigen HA-1 3.03E-32 -22.81 BE349017 Hs.196914

61 218454_at FLJ22662 hypothetical protein FLJ22662 8.93E-89 -22.76 NM_024829.1 Hs.178470

62 219183_s_at PSCD4

pleckstrin homology, Sec7 and coiled/coil

domains 4 9.71E-68 -22.70 NM_013385.2 Hs.7189

63 237647_at ESTs 1.19E-27 22.58 AI702963 Hs.202345

64 208438_s_at FGR

Gardner-Rasheed feline sarcoma viral

(v-fgr) oncogene homolog 5.45E-58 -22.56 NM_005248.1 Hs.1422

65 231688_at ESTs 3.33E-87 -22.46 AW337833 Hs.255877

66 225386_s_at LOC92906 hypothetical protein BC008217 4.33E-63 -22.18 AI559701 Hs.91684

67 213150_at HOXA10 homeo box A10 4.05E-85 -22.14 NM_018951.1 Hs.110637

68 208771_s_at LTA4H leukotriene A4 hydrolase 7.84E-54 -22.12 J02959.1 Hs.81118

(4)

70 211654_x_at HLA-DQB1

major histocompatibility complex, class II,

DQ beta 1 4.76E-83 -22.09 M17565.1 Hs.73931

71 213587_s_at LOC155066 vacuolar proton-ATPase subunit 1.40E-37 -21.94 AI884867 Hs.351612

72 226818_at LOC219972 hypothetical protein LOC219972 1.92E-83 -21.94 T64884 Hs.288581

73 226425_at FLJ21069 hypothetical protein FLJ21069 1.52E-66 -21.85 AU144247 Hs.341806

74 206676_at CEACAM8

carcinoembryonic antigen-related cell

adhesion molecule 8 5.88E-83 -21.81 M33326.1 Hs.41

75 207857_at LILRA2

leukocyte immunoglobulin-like receptor,

subfamily A (with TM domain), member 2 1.54E-50 -21.74 NM_006866.1 Hs.94498

76 211336_x_at LILRB1

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains),

member 1 2.23E-75 -21.60 AF009007.1 Hs.204040

77 204961_s_at NCF1

neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease,

autosomal 1) 6.23E-78 -21.54 NM_000265.1 Hs.1583

78 212611_at KIAA0937 KIAA0937 protein 1.90E-75 -21.54 AV728526 Hs.62264

79 225897_at

Homo sapiens mRNA, 3'UTR,

up-regulated by BCG-CWS. 1.14E-74 -21.48 AI709406 Hs.330716

80 204069_at MEIS1

Meis1, myeloid ecotropic viral integration

site 1 homolog (mouse) 5.10E-81 -21.48 NM_002398.1 Hs.170177 81 226545_at

Homo sapiens mRNA; cDNA DKFZp586E1624 (from clone

DKFZp586E1624) 5.61E-81 -21.46 AL110152.1 Hs.94030

82 222496_s_at FLJ20273 RNA-binding protein 4.83E-63 -21.43 AW241742 Hs.95549

83 228760_at

ESTs, Weakly similar to RNA polymerase I subunit [Homo sapiens]

[H.sapiens] 5.47E-40 -21.40 AV725947 Hs.438784

84 223663_at FLJ37970 hypothetical protein FLJ37970 5.19E-32 -21.38 AL136799.1 Hs.98564

85 214789_x_at SRP46 Splicing factor, arginine/serine-rich, 46kD 1.29E-30 -21.30 AA524274 Hs.155160

86 211657_at CEACAM6

carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross

reacting antigen) 8.42E-80 -21.29 M18728.1 Hs.73848

87 228153_at LOC255488 hypothetical protein LOC255488 1.05E-73 -21.21 AI953847 Hs.294092

88 210784_x_at LILRB3

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains),

(5)

89 215193_x_at HLA-DRB1

major histocompatibility complex, class II,

DR beta 1 3.81E-43 -21.18 AJ297586.1 Hs.375570

90 224918_x_at MGST1 microsomal glutathione S-transferase 1 7.63E-25 21.16 AI220117 Hs.389700

91 203932_at HLA-DMB

major histocompatibility complex, class II,

DM beta 1.56E-67 -21.07 NM_002118.1 Hs.1162

92 228370_at SNURF SNRPN upstream reading frame 1.89E-50 -21.07 BF114870 Hs.58606

93 233031_at

Homo sapiens HSPC082 mRNA, partial

cds 4.29E-34 -21.06 AV739670 Hs.283930

94 204393_s_at ACPP acid phosphatase, prostate 3.31E-68 -21.05 NM_001099.2 Hs.1852

95 217388_s_at KYNU kynureninase (L-kynurenine hydrolase) 6.71E-76 -21.03 D55639.1 Hs.169139

96 209905_at HOXA9 homeo box A9 1.26E-77 -21.01 AI246769 Hs.127428

97 241742_at PRAM-1 PRAM-1 protein 7.71E-54 -20.99 AW027174 Hs.239276

98 208650_s_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 1.28E-69 -20.97 BG327863 Hs.375108

99 206584_at LY96 lymphocyte antigen 96 1.01E-67 -20.97 NM_015364.1 Hs.69328

(6)

list_2 AML with t(8;21) versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 221581_s_at WBSCR5

Williams-Beuren syndrome chromosome

region 5 5.02E-107 -30.94 AF257135.1 Hs.56607

2 224764_at ARHGAP10 Rho-GTPase activating protein 10 4.46E-96 -29.01 AB037845.1 Hs.11611

3 217963_s_at NGFRAP1

nerve growth factor receptor

(TNFRSF16) associated protein 1 1.12E-124 -28.77 NM_014380.1 Hs.381039

4 205453_at HOXB2 homeo box B2 4.28E-102 -25.27 NM_002145.1 Hs.2733

5 208146_s_at CPVL carboxypeptidase, vitellogenic-like 2.02E-99 -25.16 NM_031311.1 Hs.95594

6 228559_at

Homo sapiens, clone IMAGE:6043059,

mRNA 2.39E-73 -24.04 BF111626 Hs.55028

7 215087_at

Homo sapiens mRNA full length insert

cDNA clone EUROIMAGE 68600. 1.57E-47 -23.05 AL109730.1 Hs.306331

8 216801_at

Homo sapiens cDNA: FLJ23257 fis,

clone COL05579. 9.69E-69 -22.79 AK026910.1 Hs.367840

9 214651_s_at HOXA9 homeo box A9 4.15E-85 -22.76 U41813.1 Hs.127428

10 203741_s_at ADCY7 adenylate cyclase 7 3.34E-42 -22.00 NM_001114.1 Hs.172199

11 238012_at

Homo sapiens, Similar to mannosidase, alpha, class 1B, member 1, clone

IMAGE:3623379, mRNA 7.35E-40 -21.89 AI620209 Hs.37916

12 217975_at LOC51186 pp21 homolog 3.50E-58 -21.28 NM_016303.1 Hs.15984

13 204069_at MEIS1

Meis1, myeloid ecotropic viral integration

site 1 homolog (mouse) 7.87E-77 -20.98 NM_002398.1 Hs.170177

14 211737_x_at PTN

pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor

1) 2.97E-58 -20.97 BC005916.1 Hs.44

15 235753_at

Homo sapiens cDNA FLJ34835 fis, clone

NT2NE2010150. 2.42E-71 -20.72 AI492051 Hs.196169

16 208091_s_at DKFZP564K0822 hypothetical protein DKFZp564K0822 2.62E-71 -20.29 NM_030796.1 Hs.4750

17 204030_s_at SCHIP1 schwannomin interacting protein 1 6.17E-72 -20.20 NM_014575.1 Hs.61490

18 209905_at HOXA9 homeo box A9 6.98E-72 -20.16 AI246769 Hs.127428

19 213147_at HOXA10 homeo box A10 5.60E-49 -19.98 NM_018951.1 Hs.110637

20 212895_s_at ABR active BCR-related gene 5.03E-31 -19.51 AL527773 Hs.118021

21 206310_at SPINK2

serine protease inhibitor, Kazal type, 2

(7)

22 213908_at

Homo sapiens, clone IMAGE:4837016,

mRNA 4.71E-44 -19.29 AI824078 Hs.362800

23 213165_at

Homo sapiens clone CDABP0086 mRNA

sequence 6.03E-44 -19.27 AI041204 Hs.323748

24 228988_at ZNF6 zinc finger protein 6 (CMPX1) 1.47E-65 -19.07 AU157017 Hs.326801

25 204057_at ICSBP1

interferon consensus sequence binding

protein 1 3.12E-53 -18.96 AI073984 Hs.14453

26 204494_s_at DKFZP434H132 DKFZP434H132 protein 1.92E-31 -18.95 AW516789 Hs.17936

27 230894_s_at

Homo sapiens, clone IMAGE:4154313,

mRNA, partial cds 1.31E-44 -18.86 BE672557 Hs.173179

28 225240_s_at

Homo sapiens, clone IMAGE:4154313,

mRNA, partial cds 1.74E-48 -18.85 BF435123 Hs.173179

29 228570_at FLJ33957 hypothetical protein FLJ33957 9.63E-37 -18.82 BF510581 Hs.271272

30 228365_at LOC144402 copine VIII 1.37E-52 -18.78 AI765180 Hs.71818

31 223286_at HSPC002 HSPC002 protein 7.64E-41 -18.62 BC002762.1 Hs.76907

32 240572_s_at

Homo sapiens cDNA FLJ38955 fis, clone

NT2RI2000107. 1.82E-59 -18.44 BF436632 Hs.156100

33 224724_at SULF2 similar to glucosamine-6-sulfatases 8.83E-59 -18.34 AL133001.1 Hs.43857

34 224367_at DJ79P11.1 X-linked protein 2.59E-57 -18.32 AF251053.1 Hs.283719

35 218608_at HSA9947 putative ATPase 6.71E-33 -18.28 NM_022089.1 Hs.128866

36 204495_s_at DKFZP434H132 DKFZP434H132 protein 1.55E-29 -18.24 NM_015492.1 Hs.17936

37 203505_at ABCA1

ATP-binding cassette, sub-family A

(ABC1), member 1 1.27E-52 -18.08 AF285167.1 Hs.211562

38 213150_at HOXA10 homeo box A10 1.36E-43 -18.02 NM_018951.1 Hs.110637

39 212423_at FLJ90798 hypothetical protein FLJ90798 3.11E-28 -17.98 AL049949.1 Hs.28264

40 204000_at GNB5

guanine nucleotide binding protein (G

protein), beta 5 1.15E-38 -17.95 NM_016194.1 Hs.155090

41 224436_s_at DKFZp564D177 DKFZp564D177 protein 7.12E-25 -17.88 BC005935.1 Hs.24608

42 224595_at CDW92 CDw92 antigen 1.29E-33 -17.81 NM_022109.1 Hs.179902

43 238756_at

Homo sapiens cDNA FLJ35212 fis, clone

PROST1000136. 2.26E-42 -17.81 AI860012 Hs.41294

44 226134_s_at

Homo sapiens, clone IMAGE:4154313,

mRNA, partial cds 3.19E-39 -17.75 AI978754 Hs.173179

45 206478_at KIAA0125 KIAA0125 gene product 1.13E-57 -17.72 NM_014792.1 Hs.38365

46 216616_at

Homo sapiens mRNA; cDNA DKFZp761N1323 (from clone

(8)

47 225227_at

Homo sapiens, clone IMAGE:5299642,

mRNA 5.48E-43 -17.67 AW294869 Hs.17132

48 238778_at FLJ32798 hypothetical protein FLJ32798 5.13E-40 -17.62 AI244661 Hs.350684

49 233555_s_at SULF2 similar to glucosamine-6-sulfatases 1.53E-52 -17.61 AL034418 Hs.43857

50 225615_at LOC126917 hypothetical protein LOC126917 7.97E-28 -17.56 AK024480.1 Hs.13766

51 213385_at CHN2 chimerin (chimaerin) 2 6.39E-44 -17.43 AK026415.1 Hs.286055

52 235521_at HOXA3 homeo box A3 9.96E-56 -17.37 AW137982 Hs.248074

53 220066_at CARD15

caspase recruitment domain family,

member 15 7.57E-35 -17.34 NM_022162.1 Hs.135201

54 212774_at ZNF238 zinc finger protein 238 9.61E-24 -17.32 AJ223321 Hs.69997

55 202318_s_at SUSP1 SUMO-1-specific protease 8.78E-28 -17.25 AF306508.1 Hs.27197

56 243010_at MSI2 musashi homolog 2 (Drosophila) 1.06E-33 -17.16 BE000929 Hs.103512

57 213555_at MGC13523 hypothetical protein MGC13523 2.10E-26 -17.16 AL049699 Hs.423336

58 204487_s_at KCNQ1

potassium voltage-gated channel,

KQT-like subfamily, member 1 8.63E-28 -17.11 NM_000218.1 Hs.156115

59 203680_at PRKAR2B

protein kinase, cAMP-dependent,

regulatory, type II, beta 4.22E-34 -17.10 NM_002736.1 Hs.77439

60 211597_s_at HOP homeodomain-only protein 2.67E-52 -17.10 AB059408.1 Hs.13775

61 218236_s_at PRKCN protein kinase C, nu 1.08E-26 -17.04 NM_005813.2 Hs.143460

62 219165_at PDLIM2 PDZ and LIM domain 2 (mystique) 1.42E-25 -17.01 NM_021630.1 Hs.379109

63 229971_at GPR114 G protein-coupled receptor 114 6.29E-34 -17.00 BF057784 Hs.301930

64 214146_s_at PPBP

pro-platelet basic protein (chemokine

(C-X-C motif) ligand 7) 1.78E-49 -16.95 R64130 Hs.2164

65 235391_at LOC137392 similar to CG6405 gene product 4.48E-44 -16.88 AW960748 Hs.403869

66 204202_at KIAA1023 KIAA1023 protein 1.75E-23 -16.84 NM_017604.1 Hs.21361

67 224049_at KCNK17

potassium channel, subfamily K, member

17 7.57E-35 -16.83 AF339912.1 Hs.162282

68 219183_s_at PSCD4

pleckstrin homology, Sec7 and coiled/coil

domains 4 4.60E-37 -16.82 NM_013385.2 Hs.7189

69 203521_s_at ZFP318 endocrine regulator 1.18E-29 -16.81 NM_014345.1 Hs.48433

70 227388_at

Homo sapiens, similar to putative, clone

IMAGE:5190302, mRNA, partial cds 8.96E-46 -16.59 AA479016 Hs.26268 71 220377_at C14orf110 chromosome 14 open reading frame 110 4.60E-51 -16.57 NM_014151.1 Hs.128155

(9)

73 216147_at

Homo sapiens mRNA; cDNA DKFZp761L23121 (from clone

DKFZp761L23121) 5.35E-23 -16.43 AL353942.1 Hs.306504

74 226865_at

ESTs, Moderately similar to hypothetical protein FLJ20378 [Homo sapiens]

[H.sapiens] 1.14E-30 -16.38 AW130600 Hs.99472

75 212314_at KIAA0746 KIAA0746 protein 1.81E-41 -16.32 AB018289.1 Hs.49500

76 243806_at ESTs 1.56E-31 -16.29 AW015140 Hs.443007

77 233467_s_at PHEMX pan-hematopoietic expression 2.58E-21 -16.29 AF176071.1 Hs.271954

78 56256_at CGI-40 CGI-40 protein 8.59E-32 -16.29 AA150165 Hs.33724

79 210831_s_at PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.62E-22 -16.05 L27489.1 Hs.170917

80 226101_at PRKCE protein kinase C, epsilon 3.57E-46 -15.96 AI093546 Hs.211592

81 233955_x_at HSPC195 hypothetical protein HSPC195 1.36E-27 -15.91 AK001782.1 Hs.15093

82 238077_at MGC27385 hypothetical protein MGC27385 2.60E-23 -15.91 T75480 Hs.13982

83 225009_at CKLFSF4 chemokine-like factor super family 4 5.37E-30 -15.69 AA191708 Hs.325825

84 201936_s_at EIF4G3

eukaryotic translation initiation factor 4

gamma, 3 4.13E-26 -15.68 NM_003760.2 Hs.25732

85 212070_at GPR56 G protein-coupled receptor 56 1.14E-39 -15.66 AL554008 Hs.6527

86 212463_at

Homo sapiens mRNA; cDNA DKFZp564J0323 (from clone

DKFZp564J0323) 2.66E-25 -15.65 BE379006 Hs.99766

87 204293_at SGSH

N-sulfoglucosamine sulfohydrolase

(sulfamidase) 2.99E-46 -15.63 NM_000199.1 Hs.31074

88 214450_at CTSW cathepsin W (lymphopain) 3.69E-40 -15.63 NM_001335.1 Hs.87450

89 203949_at MPO myeloperoxidase 7.50E-19 15.62 NM_000250.1 Hs.1817

90 237381_at

Homo sapiens, clone IMAGE:5167766,

mRNA 6.56E-24 -15.59 AW207390 Hs.39557

91 230264_s_at AP1S2

adaptor-related protein complex 1, sigma

2 subunit 5.26E-30 -15.57 AA551090 Hs.40368

92 225252_at C20orf139 chromosome 20 open reading frame 139 1.61E-32 -15.49 AL121758 Hs.135056

93 205366_s_at HOXB6 homeo box B6 1.86E-45 -15.49 NM_018952.1 Hs.98428

94 207124_s_at GNB5

guanine nucleotide binding protein (G

protein), beta 5 1.02E-28 -15.47 NM_006578.1 Hs.155090

95 218854_at SART2

squamous cell carcinoma antigen

recognized by T cell 2.52E-28 -15.47 NM_013352.1 Hs.58636

(10)

97 237591_at ESTs 5.99E-25 -15.43 AI821565 Hs.441601

98 221606_s_at 2.30E-26 -15.43 BC005342.1

99 203504_s_at ABCA1

ATP-binding cassette, sub-family A

(ABC1), member 1 2.06E-31 -15.39 NM_005502.1 Hs.211562

(11)

list_3 AML with inv(16) versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 240423_at

Homo sapiens cDNA FLJ12744 fis, clone

NT2RP2000715. 4.01E-94 -27.65 R54953 Hs.139425

2 212463_at

Homo sapiens mRNA; cDNA DKFZp564J0323 (from clone

DKFZp564J0323) 1.24E-97 -27.43 BE379006 Hs.99766

3 237655_at ESTs 6.31E-83 -26.47 BF510450 Hs.280333

4 222558_at P15RS hypothetical protein FLJ10656 2.34E-47 -26.31 T79568 Hs.300906

5 218414_s_at NUDE1

LIS1-interacting protein NUDE1, rat

homolog 3.07E-54 -25.33 NM_017668.1 Hs.263925

6 224958_at KIAA1321 KIAA1321 protein 3.40E-86 -25.05 AI743689 Hs.24336

7 227567_at

Homo sapiens, clone IMAGE:4797078,

mRNA 3.01E-54 -24.68 AL524467 Hs.443457

8 209406_at BAG2 BCL2-associated athanogene 2 2.52E-66 -23.83 AF095192.1 Hs.55220

9 234357_at 1.05E-85 -23.53 AK023640.1

10 218332_at BEX1 brain expressed, X-linked 1 8.28E-91 -23.26 NM_018476.1 Hs.334370

11 217263_x_at 7.01E-72 -22.71 S76346.1

12 225099_at LOC200933 hypothetical protein LOC200933 3.17E-86 -22.54 AK025697.1 Hs.6994

13 213353_at ABCA5

ATP-binding cassette, sub-family A

(ABC1), member 5 3.91E-51 -22.26 BF693921 Hs.180513

14 213241_at

Homo sapiens cDNA FLJ36416 fis, clone

THYMU2011053. 1.56E-84 -22.24 AF035307.1 Hs.184697

15 204198_s_at RUNX3 runt-related transcription factor 3 8.33E-46 -21.52 AA541630 Hs.170019

16 225055_at DKFZp667M2411 hypothetical protein DKFZp667M2411 2.54E-41 -21.47 AV735241 Hs.190488

17 218927_s_at C4S-2 chondroitin 4-O-sulfotransferase 2 2.36E-54 -21.45 NM_018641.1 Hs.25204

18 211031_s_at CYLN2 cytoplasmic linker 2 1.67E-78 -21.39 BC006259.1 Hs.104717

19 213908_at

Homo sapiens, clone IMAGE:4837016,

mRNA 3.51E-61 -20.99 AI824078 Hs.362800

20 222786_at C4S-2 chondroitin 4-O-sulfotransferase 2 1.78E-45 -20.89 BC002918.1 Hs.25204

21 218795_at ACP6 lysophosphatidic acid phosphatase 1.17E-44 -20.83 NM_016361.1 Hs.15871

22 210425_x_at GOLGIN-67 golgin-67 2.43E-63 -20.55 AF164622.1 Hs.182982

23 235391_at LOC137392 similar to CG6405 gene product 1.21E-70 -20.54 AW960748 Hs.403869

24 224952_at DKFZP564D166 putative ankyrin-repeat containing protein 2.12E-33 -19.66 BF115054 Hs.4996 25 235753_at

Homo sapiens cDNA FLJ34835 fis, clone

(12)

26 204197_s_at RUNX3 runt-related transcription factor 3 2.39E-43 -19.49 NM_004350.1 Hs.170019 27 229202_at

Homo sapiens cDNA FLJ36926 fis, clone

BRACE2005196. 3.68E-55 -19.44 AI768826 Hs.137396

28 216920_s_at TRGV9 T cell receptor gamma variable 9 2.87E-49 -19.42 M27331.1 Hs.112259

29 218456_at EEG1 EEG1 5.16E-57 -19.35 NM_023925.1 Hs.234355

30 223044_at SLC11A3

solute carrier family 11 (proton-coupled divalent metal ion transporters), member

3 2.35E-44 -19.25 AL136944.1 Hs.5944

31 205830_at CLGN calmegin 1.90E-50 -19.19 NM_004362.1 Hs.86368

32 214651_s_at HOXA9 homeo box A9 7.49E-60 -19.03 U41813.1 Hs.127428

33 221959_at MGC39325 hypothetical protein MGC39325 1.00E-64 -18.94 AK026141.1 Hs.34054

34 209905_at HOXA9 homeo box A9 1.88E-64 -18.89 AI246769 Hs.127428

35 213002_at MARCKS

myristoylated alanine-rich protein kinase

C substrate 6.76E-48 -18.88 BF347326 Hs.75607

36 218872_at TSC hypothetical protein FLJ20607 3.30E-48 -18.84 NM_017899.1 Hs.18791

37 224367_at DJ79P11.1 X-linked protein 1.12E-60 -18.83 AF251053.1 Hs.283719

38 211144_x_at TRG T cell receptor gamma locus 4.61E-51 -18.62 M30894.1 Hs.407442

39 228345_at

ESTs, Moderately similar to cystein-rich hydrophobic domain 2; BRX-like-translocated in leukemia; BRX-like translocated in leukemia; cysteine-rich hydrophobic 2 [Homo sapiens]

[H.sapiens] 8.34E-42 -18.57 AI745136 Hs.34656

40 215806_x_at TRGC2 T cell receptor gamma constant 2 7.16E-44 -18.38 M13231.1 Hs.274509

41 237496_at

ESTs, Weakly similar to cytokine receptor-like factor 2; cytokine receptor CRL2 precusor [Homo sapiens]

[H.sapiens] 1.15E-28 -18.23 AI821404 Hs.227505

42 223471_at RAB3IP RAB3A interacting protein (rabin3) 1.66E-28 -18.21 BC002556.1 Hs.103267

43 228155_at MGC4248 hypothetical protein MGC4248 5.04E-57 -18.16 BF512388 Hs.334437

44 209813_x_at TRGV9 T cell receptor gamma variable 9 6.45E-45 -18.07 M16768.1 Hs.112259

45 225102_at LOC152009 hypothetical protein LOC152009 3.59E-36 -17.85 BG168471 Hs.3964

46 214146_s_at PPBP

pro-platelet basic protein (chemokine

(C-X-C motif) ligand 7) 2.86E-57 -17.75 R64130 Hs.2164

47 224435_at MGC4248 hypothetical protein MGC4248 1.31E-56 -17.71 BC005871.1 Hs.334437

48 220668_s_at DNMT3B

DNA (cytosine-5-)-methyltransferase 3

beta 1.99E-41 -17.49 NM_006892.1 Hs.251673

(13)

50 213779_at LOC129080 putative emu1 2.11E-38 -17.29 AL031186 Hs.289106

51 232611_at LOC92497 hypothetical protein LOC92497 1.96E-46 -17.13 AL137680.1 Hs.159385

52 238127_at

Homo sapiens cDNA FLJ35543 fis, clone

SPLEN2002957. 8.44E-42 -17.00 AI479082 Hs.168457

53 212070_at GPR56 G protein-coupled receptor 56 4.52E-53 -16.98 AL554008 Hs.6527

54 243010_at MSI2 musashi homolog 2 (Drosophila) 5.51E-39 -16.95 BE000929 Hs.103512

55 227929_at

Homo sapiens cDNA FLJ12935 fis, clone

NT2RP2004982. 2.45E-49 -16.90 AU151342 Hs.22545

56 229194_at

Homo sapiens, clone IMAGE:5273745,

mRNA 4.92E-36 -16.87 AL045882 Hs.432602

57 230896_at

Homo sapiens cDNA FLJ35632 fis, clone

SPLEN2011678. 3.36E-53 -16.86 AA833830 Hs.120591

58 229215_at ASCL2

achaete-scute complex-like 2

(Drosophila) 1.40E-34 -16.77 AI393930 Hs.152475

59 210976_s_at PFKM phosphofructokinase, muscle 4.22E-37 -16.75 U24183.1 Hs.75160

60 203556_at KIAA0854 KIAA0854 protein 3.57E-48 -16.73 NM_014943.1 Hs.30209

61 225240_s_at

Homo sapiens, clone IMAGE:4154313,

mRNA, partial cds 4.49E-36 -16.62 BF435123 Hs.173179

62 208886_at H1F0 H1 histone family, member 0 3.84E-34 -16.58 BC000145.1 Hs.226117

63 209193_at PIM1 pim-1 oncogene 2.53E-31 -16.52 M24779.1 Hs.81170

64 266_s_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 2.21E-38 -16.51 L33930 Hs.375108

65 218477_at PTD011 PTD011 protein 4.53E-29 -16.50 NM_014051.1 Hs.94896

66 203216_s_at MYO6 myosin VI 9.80E-46 -16.45 NM_004999.1 Hs.118483

67 226120_at TTC8 tetratricopeptide repeat domain 8 2.08E-28 -16.43 AW293939 Hs.55158

68 241706_at LOC144402 copine VIII 4.52E-34 -16.39 AA431782 Hs.71818

69 225242_s_at

Homo sapiens, clone IMAGE:4874518,

mRNA 1.31E-20 16.33 BG253437 Hs.356289

70 218418_s_at KIAA1518 KIAA1518 protein 1.01E-40 -16.22 NM_015493.1 Hs.284208

71 204160_s_at ENPP4

ectonucleotide

pyrophosphatase/phosphodiesterase 4

(putative function) 3.40E-34 -16.21 AW194947 Hs.54037

72 219218_at FLJ23058 hypothetical protein FLJ23058 4.06E-40 -16.19 NM_024696.1 Hs.98968

73 235521_at HOXA3 homeo box A3 2.02E-49 -16.18 AW137982 Hs.248074

74 208798_x_at GOLGIN-67 golgin-67 4.71E-33 -16.17 AF204231.1 Hs.182982

75 203925_at GCLM

glutamate-cysteine ligase, modifier

subunit 4.56E-47 -16.15 NM_002061.1 Hs.89709

(14)

77 225864_at

Homo sapiens cDNA FLJ23705 fis, clone

HEP11066. 6.83E-39 -16.09 AL039862 Hs.49136

78 226134_s_at

Homo sapiens, clone IMAGE:4154313,

mRNA, partial cds 1.38E-32 -15.99 AI978754 Hs.173179

79 212314_at KIAA0746 KIAA0746 protein 2.88E-46 -15.99 AB018289.1 Hs.49500

80 226352_at

Homo sapiens cDNA FLJ35156 fis, clone

PLACE6011057. 6.58E-29 -15.96 BF447037 Hs.294110

81 214464_at CDC42BPA

CDC42 binding protein kinase alpha

(DMPK-like) 8.47E-48 -15.95 NM_003607.1 Hs.18586

82 209094_at DDAH1

dimethylarginine dimethylaminohydrolase

1 2.90E-42 -15.95 AL078459 Hs.380870

83 209447_at SYNE1

spectrin repeat containing, nuclear

envelope 1 8.77E-40 -15.94 AF043290.1 Hs.192102

84 235759_at STIP-1 synaptotagmin interacting protein 1 5.93E-46 -15.90 AI095542 Hs.302754

85 213110_s_at COL4A5

collagen, type IV, alpha 5 (Alport

syndrome) 1.41E-47 -15.87 AW052179 Hs.169825

86 213737_x_at

Homo sapiens, clone IMAGE:4133122,

mRNA 1.29E-29 -15.86 AI620911 Hs.50787

87 238365_s_at

ESTs, Weakly similar to CA13_MOUSE Collagen alpha 1(III) chain precursor

[M.musculus] 7.88E-38 -15.85 AW015512 Hs.158272

88 235089_at MGC15482 hypothetical protein MGC15482 5.35E-34 -15.81 AI122770 Hs.194498

89 204411_at KIAA0449 KIAA0449 protein 1.82E-43 -15.80 NM_017596.1 Hs.169182

90 217963_s_at NGFRAP1

nerve growth factor receptor

(TNFRSF16) associated protein 1 8.09E-28 -15.79 NM_014380.1 Hs.381039

91 206440_at LIN7A lin-7 homolog A (C. elegans) 2.15E-38 -15.76 NM_004664.1 Hs.416087

92 204720_s_at DNAJC6

DnaJ (Hsp40) homolog, subfamily C,

member 6 6.57E-44 -15.72 AV729634 Hs.44896

93 209771_x_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 1.25E-30 -15.70 AA761181 Hs.375108

94 218445_at H2AFY2 H2A histone family, member Y2 1.69E-37 -15.70 NM_018649.1 Hs.92023

95 204976_s_at AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis

chromosomal region, gene 1 1.86E-45 -15.68 AK023637.1 Hs.326142

96 211026_s_at MGLL monoglyceride lipase 3.45E-30 -15.65 BC006230.1 Hs.6721

97 208797_s_at GOLGIN-67 golgin-67 1.35E-27 -15.65 AI829170 Hs.182982

(15)

99 219304_s_at SCDGF-B spinal cord-derived growth factor-B 2.15E-38 -15.63 NM_025208.1 Hs.112885 100 230894_s_at

Homo sapiens, clone IMAGE:4154313,

(16)

list_4

AML with normal karyotype or so-called “other” cytogenetic abnormalities versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 205366_s_at HOXB6 homeo box B6 6.22E-41 16.06 NM_018952.1 Hs.98428

2 205453_at HOXB2 homeo box B2 9.29E-41 15.44 NM_002145.1 Hs.2733

3 228904_at ESTs 6.22E-38 15.24 AW510657 Hs.156044

4 236892_s_at

Homo sapiens, clone MGC:10077

IMAGE:3896690, mRNA, complete cds 8.35E-37 14.99 BF590528 Hs.183096

5 205601_s_at HOXB5 homeo box B5 5.82E-38 14.75 NM_002147.1 Hs.22554

6 227853_at

ESTs, Weakly similar to I60307 beta-galactosidase, alpha peptide -

Escherichia coli [E. coli] 3.35E-38 14.54 AW024350 Hs.356538

7 239791_at

Homo sapiens, clone MGC:10077

IMAGE:3896690, mRNA, complete cds 4.43E-35 14.48 AI125255 Hs.183096

8 205600_x_at HOXB5 homeo box B5 6.17E-37 14.47 AI052747 Hs.22554

9 211984_at

Homo sapiens, clone IMAGE:5301034,

mRNA 1.75E-36 -13.89 AI653730 Hs.374441

10 239651_at ANAPC5 anaphase promoting complex subunit 5 4.93E-36 13.76 BE671583 Hs.7101

11 208623_s_at VIL2 villin 2 (ezrin) 1.16E-34 -13.67 J05021.1 Hs.155191

12 224964_s_at GNG2

guanine nucleotide binding protein (G

protein), gamma 2 1.31E-35 -13.66 AU118419 Hs.289026

13 211985_s_at

Homo sapiens, clone IMAGE:5301034,

mRNA 1.32E-34 -13.45 AI653730 Hs.374441

14 224609_at CTL2 CTL2 gene 6.62E-34 -13.34 AI264216 Hs.105509

15 231767_at HOXB4 homeo box B4 1.99E-31 13.33 AL137449.1 Hs.126666

16 225175_s_at CTL2 CTL2 gene 3.19E-33 -13.14 AI569503 Hs.105509

17 206398_s_at CD19 CD19 antigen 5.33E-31 -12.96 NM_001770.1 Hs.96023

18 206295_at IL18

interleukin 18

(interferon-gamma-inducing factor) 3.25E-31 12.94 NM_001562.1 Hs.83077

19 230743_at

Homo sapiens, clone MGC:10077

IMAGE:3896690, mRNA, complete cds 7.43E-30 12.92 AI743312 Hs.183096

(17)

21 214651_s_at HOXA9 homeo box A9 3.00E-31 12.86 U41813.1 Hs.127428

22 213326_at VAMP1

vesicle-associated membrane protein 1

(synaptobrevin 1) 1.14E-31 -12.86 AU150319 Hs.20021

23 221726_at RPL22 ribosomal protein L22 8.92E-31 12.75 BE250348 Hs.326249

24 221558_s_at LEF1 lymphoid enhancer-binding factor 1 2.66E-30 -12.68 AF288571.1 Hs.44865

25 207100_s_at VAMP1

vesicle-associated membrane protein 1

(synaptobrevin 1) 7.59E-31 -12.62 NM_016830.1 Hs.20021

26 210024_s_at UBE2E3

ubiquitin-conjugating enzyme E2E 3

(UBC4/5 homolog, yeast) 2.75E-30 12.58 AB017644.1 Hs.4890

27 209563_x_at CALM1

calmodulin 1 (phosphorylase kinase,

delta) 9.35E-31 -12.58 BC000454.1 Hs.282410

28 228057_at LOC115265 similar to Smhs1 protein 2.07E-30 12.55 AA528140 Hs.107515

29 243819_at ESTs 2.49E-30 -12.49 AU146329 Hs.187772

30 226123_at LOC286180 hypothetical protein LOC286180 2.14E-30 -12.49 AI870918 Hs.397426

31 215235_at SPTAN1

spectrin, alpha, non-erythrocytic 1

(alpha-fodrin) 3.67E-30 -12.45 AL110273.1 Hs.77196

32 211890_x_at CAPN3 calpain 3, (p94) 7.43E-30 -12.43 AF127765.3 Hs.293267

33 215051_x_at AIF1 allograft inflammatory factor 1 7.46E-30 12.41 BF213829 Hs.76364

34 204615_x_at IDI1 isopentenyl-diphosphate delta isomerase 5.26E-30 -12.40 NM_004508.1 Hs.76038

35 230659_at KIAA0212 KIAA0212 gene product 6.21E-30 -12.38 AW139300 Hs.154332

36 208881_x_at IDI1 isopentenyl-diphosphate delta isomerase 2.46E-29 -12.24 BC005247.1 Hs.76038

37 214475_x_at CAPN3 calpain 3, (p94) 5.59E-29 -12.24 AF127764.1 Hs.293267

38 207233_s_at MITF

microphthalmia-associated transcription

factor 1.86E-28 12.20 NM_000248.1 Hs.166017

39 224741_x_at

Homo sapiens mRNA; cDNA DKFZp564D0164 (from clone

DKFZp564D0164) 1.85E-28 12.17 BG329175 Hs.289721

40 224767_at

Homo sapiens mRNA; cDNA DKFZp434J0428 (from clone

DKFZp434J0428) 8.73E-28 12.13 AL137450.1 Hs.80545

41 220367_s_at FLJ12761 hypothetical protein FLJ12761 1.32E-28 -12.11 NM_024545.1 Hs.10554

42 221969_at PAX5

paired box gene 5 (B-cell lineage specific

activator protein) 3.59E-27 -11.98 BF510692 Hs.22030

43 209949_at NCF2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease,

(18)

44 212531_at LCN2 lipocalin 2 (oncogene 24p3) 1.04E-27 -11.97 NM_005564.1 Hs.204238

45 212242_at TUBA1 tubulin, alpha 1 (testis specific) 3.72E-28 -11.97 AL565074 Hs.75318

46 212071_s_at SPTBN1 spectrin, beta, non-erythrocytic 1 5.73E-28 -11.92 BE968833 Hs.107164

47 224841_x_at

Homo sapiens mRNA; cDNA DKFZp564D0164 (from clone

DKFZp564D0164) 2.00E-27 11.91 BF316352 Hs.289721

48 203421_at PIG11 p53-induced protein 1.22E-27 -11.89 NM_006034.1 Hs.433813

49 213147_at HOXA10 homeo box A10 2.63E-27 11.79 NM_018951.1 Hs.110637

50 213110_s_at COL4A5

collagen, type IV, alpha 5 (Alport

syndrome) 1.12E-25 11.76 AW052179 Hs.169825

51 204446_s_at ALOX5 arachidonate 5-lipoxygenase 3.08E-27 -11.74 NM_000698.1 Hs.89499

52 35974_at LRMP lymphoid-restricted membrane protein 1.74E-26 -11.73 U10485 Hs.40202

53 204674_at LRMP lymphoid-restricted membrane protein 1.74E-26 -11.72 NM_006152.1 Hs.40202

54 213095_x_at AIF1 allograft inflammatory factor 1 1.94E-26 11.70 AF299327.1 Hs.76364

55 209760_at KIAA0922 KIAA0922 protein 7.37E-27 -11.69 AL136932.1 Hs.37892

56 239344_at ESTs 2.08E-26 11.68 H23542 Hs.181788

57 204215_at MGC4175 hypothetical protein MGC4175 2.16E-26 -11.68 NM_024315.1 Hs.322404

58 223304_at DKFZp761N0624 hypothetical protein DKFZp761N0624 2.84E-26 -11.64 AL136583.1 Hs.21893

59 218205_s_at MKNK2

MAP kinase-interacting serine/threonine

kinase 2 1.03E-26 -11.62 NM_017572.1 Hs.261828

60 235753_at

Homo sapiens cDNA FLJ34835 fis, clone

NT2NE2010150. 3.92E-26 11.62 AI492051 Hs.196169

61 227182_at MGC26847 hypothetical protein MGC26847 1.57E-26 -11.62 AW966474 Hs.88417

62 238637_at

ESTs, Weakly similar to hypothetical protein FLJ20489 [Homo sapiens]

[H.sapiens] 1.55E-25 11.54 N24703 Hs.123065

63 226207_at

Homo sapiens, Similar to hypothetical protein FLJ21394, clone MGC:23917

IMAGE:4770900, mRNA, complete cds 2.27E-26 -11.53 AI358954 Hs.11700 64 241619_at

ESTs, Weakly similar to neuronal thread

protein [Homo sapiens] [H.sapiens] 2.84E-26 -11.52 BF526558 Hs.252730

65 224965_at GNG2

guanine nucleotide binding protein (G

protein), gamma 2 4.89E-26 -11.46 AU118419 Hs.289026

66 200093_s_at - HG-U133B HINT1

histidine triad nucleotide binding protein

1 2.23E-25 11.43 N32864 Hs.256697

(19)

68 223157_at MGC3232 hypothetical protein MGC3232 2.23E-25 11.41 BC004894.1 Hs.8715

69 38269_at PRKD2 protein kinase D2 2.56E-25 -11.35 AL050147 Hs.91146

70 217800_s_at NDFIP1 Nedd4 family interacting protein 1 1.77E-24 11.26 NM_030571.1 Hs.9788

71 228249_at LOC119710 hypothetical protein BC009561 6.63E-25 11.25 AA535128 Hs.406726

72 213474_at FLJ32069 hypothetical protein FLJ32069 5.36E-25 -11.21 AI890903 Hs.119683

73 207111_at EMR1

egf-like module containing, mucin-like,

hormone receptor-like sequence 1 4.19E-24 11.21 NM_001974.1 Hs.2375 74 224915_x_at

Homo sapiens, clone IMAGE:5285034,

mRNA 1.39E-24 11.21 AV756131 Hs.356766

75 226227_x_at

Homo sapiens, clone IMAGE:5285034,

mRNA 1.39E-24 11.20 BF185165 Hs.356766

76 224490_s_at 8.41E-25 -11.15 BC006271.1

77 225782_at LOC253827 hypothetical protein LOC253827 2.61E-24 11.15 BG171064 Hs.339024

78 226765_at SPTBN1 spectrin, beta, non-erythrocytic 1 1.00E-24 -11.14 AA971514 Hs.107164

79 213150_at HOXA10 homeo box A10 3.09E-24 11.12 NM_018951.1 Hs.110637

80 208072_s_at DGKD diacylglycerol kinase, delta 130kDa 1.39E-24 -11.12 NM_003648.1 Hs.115907

81 212098_at LOC151162 hypothetical protein LOC151162 2.11E-24 -11.11 AL134724 Hs.374342

82 218373_at FTS fused toes homolog (mouse) 2.58E-24 -11.11 NM_022476.1 Hs.288929

83 209659_s_at CDC16

CDC16 cell division cycle 16 homolog (S.

cerevisiae) 1.86E-24 -11.09 AF164598.1 Hs.1592

84 205049_s_at CD79A

CD79A antigen

(immunoglobulin-associated alpha) 1.29E-23 -11.05 NM_001783.1 Hs.79630

85 218922_s_at FLJ12089 hypothetical protein FLJ12089 4.58E-24 -10.99 NM_024552.1 Hs.300439

86 208826_x_at HINT1

histidine triad nucleotide binding protein

1 2.74E-23 10.90 U27143.1 Hs.256697

87 243060_at ESTs 1.50E-23 10.90 R59989 Hs.176539

88 238026_at

Homo sapiens cDNA FLJ39255 fis, clone

OCBBF2008814. 2.80E-23 10.87 AI458020 Hs.378870

89 206896_s_at GNG7

guanine nucleotide binding protein (G

protein), gamma 7 1.38E-23 -10.85 NM_005145.1 Hs.127828

90 205267_at POU2AF1

POU domain, class 2, associating factor

1 7.95E-23 -10.85 NM_006235.1 Hs.2407

91 210948_s_at LEF1 lymphoid enhancer-binding factor 1 4.23E-23 -10.84 AF294627.1 Hs.44865

92 228113_at STAT3

signal transducer and activator of transcription 3 (acute-phase response

factor) 3.40E-23 10.83 R62453 Hs.321677

93 238498_at

Homo sapiens mRNA full length insert

(20)

94 218829_s_at KIAA1416 KIAA1416 protein 2.62E-23 -10.78 NM_017780.1 Hs.105461

95 204108_at NFYA nuclear transcription factor Y, alpha 2.55E-23 -10.78 NM_002505.2 Hs.348999

96 206289_at HOXA4 homeo box A4 1.61E-22 10.78 NM_002141.1 Hs.77637

97 223306_at EBRP

emopamil binding related protein,

delta8-delta7 sterol isomerase related protein 6.04E-23 10.78 AF243433.1 Hs.433278

98 226165_at E2F5 E2F transcription factor 5, p130-binding 7.29E-23 10.76 BF674436 Hs.2331

99 212401_s_at CDC2L2 cell division cycle 2-like 2 5.90E-23 -10.75 AI767436 Hs.355896

100 225553_at

Homo sapiens cDNA FLJ12874 fis, clone

(21)

list_5

AML with 11q23/MLL rearrangement versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 225344_at ERAP140

endoplasmic reticulum associated protein

140 kDa 1.49E-42 -20.00 AL035689 Hs.339283

2 204951_at ARHH ras homolog gene family, member H 2.37E-41 -19.38 NM_004310.1 Hs.109918

3 233849_s_at ARHGAP5 Rho GTPase activating protein 5 8.54E-34 -18.62 AK023014.1 Hs.267831

4 217979_at NET-6

transmembrane 4 superfamily member

tetraspan NET-6 2.11E-50 -18.58 NM_014399.1 Hs.284243

5 221760_at MAN1A1 mannosidase, alpha, class 1A, member 1 3.07E-47 -18.51 BG287153 Hs.25253

6 208116_s_at MAN1A1 mannosidase, alpha, class 1A, member 1 5.93E-40 -17.90 NM_005907.1 Hs.25253

7 227193_at

Homo sapiens, clone IMAGE:4828750,

mRNA 2.18E-34 -17.50 AI955713 Hs.375762

8 226517_at BCAT1

branched chain aminotransferase 1,

cytosolic 5.42E-30 -16.72 AL390172.1 Hs.317432

9 206761_at TACTILE

T cell activation, increased late

expression 8.04E-46 -16.72 NM_005816.1 Hs.142023

10 204165_at WASF1 WAS protein family, member 1 1.44E-36 -16.49 NM_003931.1 Hs.75850

11 218899_s_at BAALC brain and acute leukemia, cytoplasmic 7.63E-49 -16.43 NM_024812.1 Hs.169395

12 213258_at

ESTs, Weakly similar to cytokine receptor-like factor 2; cytokine receptor CRL2 precusor [Homo sapiens]

[H.sapiens] 1.49E-41 -16.34 BF511231 Hs.87980

13 212311_at KIAA0746 KIAA0746 protein 3.06E-30 -16.20 AB018289.1 Hs.49500

14 218086_at NPDC1

neural proliferation, differentiation and

control, 1 4.28E-45 -15.67 NM_015392.1 Hs.105547

15 218856_at TNFRSF21

tumor necrosis factor receptor

superfamily, member 21 1.67E-33 -15.36 NM_016629.1 Hs.159651

16 214390_s_at BCAT1

branched chain aminotransferase 1,

cytosolic 1.27E-28 -15.17 AI652662 Hs.317432

17 230285_at DKFZp313A2432 hypothetical protein DKFZp313A2432 1.37E-27 -15.12 BF447829 Hs.349096

18 228571_at

Homo sapiens cDNA FLJ35956 fis, clone

TESTI2012289. 2.37E-31 -15.11 BE963438 Hs.379038

19 222780_s_at BAALC brain and acute leukemia, cytoplasmic 1.38E-41 -15.05 AI870583 Hs.169395

(22)

21 236198_at ESTs 1.42E-27 -14.72 AW292872 Hs.124554

22 220306_at FLJ20202 hypothetical protein FLJ20202 2.30E-22 -14.69 NM_017709.1 Hs.356216

23 225285_at

Homo sapiens cDNA: FLJ21962 fis,

clone HEP05564. 7.27E-24 -14.69 AK025615.1 Hs.7567

24 226342_at

Homo sapiens mRNA; cDNA DKFZp564N1063 (from clone

DKFZp564N1063) 4.66E-34 -14.60 AW593244 Hs.236443

25 204698_at ISG20 interferon stimulated gene 20kDa 2.52E-36 -14.40 NM_002201.2 Hs.183487

26 222455_s_at PARVA parvin, alpha 6.19E-24 -14.30 AF237771.1 Hs.44077

27 214953_s_at APP

amyloid beta (A4) precursor protein

(protease nexin-II, Alzheimer disease) 1.17E-23 -14.26 X06989.1 Hs.177486

28 209374_s_at IGHM immunoglobulin heavy constant mu 1.08E-36 -14.20 BC001872.1 Hs.153261

29 217936_at

Homo sapiens cDNA FLJ12952 fis, clone NT2RP2005476, highly similar to Human

p190-B (p190-B) mRNA. 1.88E-21 -14.19 AW044631 Hs.432517

30 212912_at

Homo sapiens, clone IMAGE:4151609,

mRNA 5.34E-26 -14.14 AI992251 Hs.184581

31 210487_at DNTT deoxynucleotidyltransferase, terminal 1.06E-37 -14.11 M11722.1 Hs.397294

32 212558_at SPRY1

sprouty homolog 1, antagonist of FGF

signaling (Drosophila) 3.02E-32 -13.91 BF508662 Hs.88044

33 205349_at GNA15

guanine nucleotide binding protein (G

protein), alpha 15 (Gq class) 2.52E-22 -13.90 NM_002068.1 Hs.73797

34 225830_at LOC118987 hypothetical protein LOC118987 2.07E-25 -13.88 BE552184 Hs.131834

35 228976_at

ESTs, Weakly similar to hypothetical protein FLJ20294 [Homo sapiens]

[H.sapiens] 9.86E-35 -13.84 AA778249 Hs.65578

36 235759_at STIP-1 synaptotagmin interacting protein 1 1.36E-32 -13.77 AI095542 Hs.302754

37 203544_s_at STAM

signal transducing adaptor molecule

(SH3 domain and ITAM motif) 1 4.92E-20 -13.69 NM_003473.1 Hs.153487

38 232985_s_at FLJ10713 hypothetical protein FLJ10713 6.18E-35 -13.65 AK022821.1 Hs.9536

39 214849_at MGC14254 hypothetical protein MGC14254 1.41E-22 -13.59 AW500220 Hs.188757

40 219648_at FLJ10116 hypothetical protein FLJ10116 2.62E-25 -13.53 NM_018000.1 Hs.79741

41 205330_at MN1

meningioma (disrupted in balanced

translocation) 1 3.30E-34 -13.52 NM_002430.1 Hs.268515

42 214581_x_at TNFRSF21

tumor necrosis factor receptor

superfamily, member 21 9.95E-25 -13.51 BE568134 Hs.159651

43 266_s_at CD24

CD24 antigen (small cell lung carcinoma

(23)

44 226223_at ESTs 3.25E-28 -13.41 AI189509 Hs.406074

45 219789_at NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide

receptor C) 2.45E-28 -13.33 AI628360 Hs.123655

46 227461_at STN2 stonin 2 6.25E-26 -13.33 AA632295 Hs.336428

47 237571_at ESTs 4.43E-25 -13.26 AI458998 Hs.170424

48 226765_at SPTBN1 spectrin, beta, non-erythrocytic 1 7.76E-23 -13.23 AA971514 Hs.107164

49 219188_s_at LRP16 LRP16 protein 7.40E-20 -13.19 NM_014067.2 Hs.10824

50 232611_at LOC92497 hypothetical protein LOC92497 7.84E-25 -13.19 AL137680.1 Hs.159385

51 208657_s_at MSF MLL septin-like fusion 2.11E-26 -13.14 AF142408.1 Hs.181002

52 208650_s_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 4.95E-22 -13.13 BG327863 Hs.375108

53 217090_at

H.sapiens mRNA for cyritestin protein

(clone T3) 8.19E-31 -13.07 X89655.1 Hs.381383

54 231969_at DKFZp762K222 hypothetical protein DKFZp762K222 1.77E-30 -13.07 AB037813.1 Hs.159200

55 214651_s_at HOXA9 homeo box A9 4.45E-16 13.07 U41813.1 Hs.127428

56 239317_at

ESTs, Weakly similar to hypothetical protein FLJ20378 [Homo sapiens]

[H.sapiens] 2.66E-32 -13.05 BG484601 Hs.282899

57 242051_at ESTs 2.58E-25 -13.04 AI695695 Hs.130260

58 214829_at AASS aminoadipate-semialdehyde synthase 1.35E-29 -13.02 AK023446.1 Hs.184168

59 211137_s_at ATP2C1

ATPase, Ca++ transporting, type 2C,

member 1 1.57E-18 -12.91 AF189723.2 Hs.106778

60 243888_at ESTs 6.76E-20 -12.89 AI610684 Hs.171088

61 220104_at ZAP zinc finger antiviral protein 1.36E-21 -12.89 NM_020119.1 Hs.35254

62 213506_at F2RL1

coagulation factor II (thrombin)

receptor-like 1 1.44E-31 -12.86 BE965369 Hs.154299

63 219686_at HSA250839 gene for serine/threonine protein kinase 1.59E-31 -12.79 NM_018401.1 Hs.58241

64 222216_s_at MRPL17 mitochondrial ribosomal protein L17 4.92E-20 -12.75 AK026857.1 Hs.10026

65 210665_at TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation

inhibitor) 3.35E-25 -12.69 AF021834.1 Hs.170279

66 210664_s_at TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation

inhibitor) 8.12E-24 -12.64 AF021834.1 Hs.170279

67 218966_at MYO5C myosin 5C 1.41E-21 -12.60 NM_018728.1 Hs.111782

(24)

69 230006_s_at DKFZp313A2432 hypothetical protein DKFZp313A2432 3.36E-19 -12.54 AI742358 Hs.349096

70 232424_at PRDM16 PR domain containing 16 1.88E-30 -12.54 AI623202 Hs.302022

71 209488_s_at RBPMS RNA binding protein with multiple splicing 6.79E-30 -12.53 D84109.1 Hs.80248

72 219090_at SLC24A3

solute carrier family 24

(sodium/potassium/calcium exchanger),

member 3 1.77E-30 -12.51 NM_020689.2 Hs.12321

73 236513_at

ESTs, Weakly similar to hypothetical protein FLJ20234 [Homo sapiens]

[H.sapiens] 1.16E-19 -12.50 AW770245 Hs.380046

74 214022_s_at MGC27165 hypothetical protein MGC27165 3.28E-19 -12.48 AA749101 Hs.366

75 209487_at RBPMS RNA binding protein with multiple splicing 4.29E-30 -12.47 D84109.1 Hs.80248

76 206398_s_at CD19 CD19 antigen 3.80E-30 -12.42 NM_001770.1 Hs.96023

77 57588_at SLC24A3

solute carrier family 24

(sodium/potassium/calcium exchanger),

member 3 1.91E-26 -12.42 R62432 Hs.12321

78 203987_at FZD6 frizzled homolog 6 (Drosophila) 2.99E-25 -12.41 NM_003506.1 Hs.114218

79 225532_at LOC91768 hypothetical protein BC004124 8.25E-21 -12.39 AK025627.1 Hs.17901

80 210875_s_at TCF8

transcription factor 8 (represses

interleukin 2 expression) 1.61E-18 -12.28 U12170.1 Hs.232068

81 212827_at IGHM immunoglobulin heavy constant mu 5.75E-28 -12.28 X17115.1 Hs.153261

82 235089_at MGC15482 hypothetical protein MGC15482 4.75E-20 -12.27 AI122770 Hs.194498

83 209772_s_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 9.51E-23 -12.27 X69397.1 Hs.375108

84 229629_at ESTs 5.92E-22 -12.26 AI923633 Hs.96886

85 222996_s_at HSPC195 hypothetical protein HSPC195 6.08E-20 -12.22 BC002490.1 Hs.15093

86 233138_at

Homo sapiens cDNA FLJ13412 fis, clone

PLACE1001745. 4.82E-25 -12.18 AU155968 Hs.178533

87 204004_at PAWR PRKC, apoptosis, WT1, regulator 7.65E-23 -12.17 AI336206 Hs.372504

88 212071_s_at SPTBN1 spectrin, beta, non-erythrocytic 1 6.49E-18 -12.16 BE968833 Hs.107164

89 212771_at LOC221061 hypothetical protein LOC221061 4.99E-28 -12.15 AU150943 Hs.66762

90 220999_s_at PRO1331 hypothetical protein PRO1331 1.00E-20 -12.14 NM_030778.1 Hs.301824

91 241756_at

Homo sapiens cDNA FLJ30650 fis, clone

CTONG2006666. 5.68E-18 -12.13 T51136 Hs.90489

92 210202_s_at BIN1 bridging integrator 1 4.03E-20 -12.13 U87558.1 Hs.193163

93 209574_s_at C18orf1 chromosome 18 open reading frame 1 9.65E-25 -12.12 AI349506 Hs.153498

(25)

95 209771_x_at CD24

CD24 antigen (small cell lung carcinoma

cluster 4 antigen) 9.74E-18 -12.10 AA761181 Hs.375108

96 209395_at CHI3L1

chitinase 3-like 1 (cartilage

glycoprotein-39) 5.27E-27 -12.07 M80927.1 Hs.75184

97 215082_at ESTs 9.67E-19 -12.06 BF973387 Hs.305989

98 232227_at

Homo sapiens HSPC324 mRNA, partial

cds 3.36E-25 -12.06 AV736391 Hs.191591

99 224516_s_at HSPC195 hypothetical protein HSPC195 2.24E-18 -12.04 BC006428.1 Hs.15093

100 203725_at GADD45A

growth arrest and

(26)

list_6

AML with complex aberrant karyotype versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 222983_s_at PAIP2 PABP-interacting protein 2 7.50E-28 -16.64 BC001716.1 Hs.396644

2 223157_at MGC3232 hypothetical protein MGC3232 3.35E-29 -15.70 BC004894.1 Hs.8715

3 222229_x_at 3.78E-22 -14.82 AL121871

4 227056_at ESTs 6.30E-21 -13.45 AA181172 Hs.446502

5 207388_s_at PTGES prostaglandin E synthase 7.93E-20 -12.73 NM_004878.1 Hs.146688

6 225433_at GTF2A1

general transcription factor IIA, 1,

19/37kDa 6.30E-21 -12.68 AU144104 Hs.299542

7 209289_at NFIB nuclear factor I/B 3.97E-20 -12.68 AI700518 Hs.33287

8 208645_s_at RPS14 ribosomal protein S14 3.18E-18 -12.35 AF116710.1 Hs.431584

9 227929_at

Homo sapiens cDNA FLJ12935 fis, clone

NT2RP2004982. 9.82E-19 -12.34 AU151342 Hs.22545

10 220787_at PRO2533 hypothetical protein PRO2533 2.70E-18 -12.27 NM_018629.1 Hs.166715

11 214919_s_at

Homo sapiens, clone IMAGE:3866125,

mRNA 1.88E-19 -12.24 R39094 Hs.301226

12 236728_at FLJ39485 hypothetical protein FLJ39485 6.66E-22 -12.13 AW070437 Hs.391318

13 218645_at ZNF277 zinc finger protein (C2H2 type) 277 9.45E-19 -12.03 NM_021994.1 Hs.42636

14 218436_at SIL1

endoplasmic reticulum chaperone SIL1,

homolog of yeast 7.93E-20 -11.94 NM_022464.1 Hs.297875

15 226694_at AKAP2 A kinase (PRKA) anchor protein 2 2.99E-22 -11.72 BG540494 Hs.42322

16 209619_at CD74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II

antigen-associated) 3.85E-18 -11.09 K01144.1 Hs.84298

17 223276_at NID67 putative small membrane protein NID67 7.79E-18 -11.06 AF313413.1 Hs.29444

18 213846_at COX7C cytochrome c oxidase subunit VIIc 1.20E-15 -10.93 AA382702 Hs.430075

19 223318_s_at MGC10974 hypothetical protein MGC10974 3.12E-17 -10.88 BC004393.1 Hs.111099

20 208646_at RPS14 ribosomal protein S14 1.22E-15 -10.79 AF116710.1 Hs.431584

21 231543_at FAPP2

phosphoinositol 4-phosphate adaptor

protein-2 5.76E-15 10.78 AI806107 Hs.233495

22 205437_at ZNF211 zinc finger protein 211 1.10E-18 -10.73 NM_006385.1 Hs.15110

23 200023_s_at - HG-U133B EIF3S5

eukaryotic translation initiation factor 3,

subunit 5 epsilon, 47kDa 9.24E-16 -10.66 NM_003754.1 Hs.7811

24 200707_at PRKCSH protein kinase C substrate 80K-H 5.42E-16 -10.63 NM_002743.1 Hs.1432

(27)

26 213622_at COL9A2 collagen, type IX, alpha 2 9.89E-20 -10.62 AI733465 Hs.37165

27 206398_s_at CD19 CD19 antigen 1.16E-20 -10.46 NM_001770.1 Hs.96023

28 210298_x_at FHL1 four and a half LIM domains 1 2.90E-14 10.38 AF098518.1 Hs.239069

29 221476_s_at RPL15 ribosomal protein L15 2.86E-14 -10.35 AF279903.1 Hs.74267

30 229693_at ESTs 4.95E-16 -10.30 AI952836 Hs.154574

31 244166_at ESTs 1.43E-16 -10.25 AI762422 Hs.248476

32 208815_x_at HSPA4 heat shock 70kDa protein 4 1.97E-15 -10.19 AB023420.1 Hs.90093

33 209259_s_at CSPG6

chondroitin sulfate proteoglycan 6

(bamacan) 1.02E-13 10.18 AF020043.1 Hs.24485

34 244360_at ESTs 4.59E-16 -10.18 AW002273 Hs.233425

35 221969_at PAX5

paired box gene 5 (B-cell lineage specific

activator protein) 9.89E-20 -10.16 BF510692 Hs.22030

36 244741_s_at

Homo sapiens, clone MGC:9913

IMAGE:3870821, mRNA, complete cds 1.79E-13 10.15 BE855713 Hs.23133

37 228083_at CACNA2D4

calcium channel, voltage-dependent,

alpha 2/delta subunit 4 9.82E-19 -10.06 AI433691 Hs.13768

38 222984_at PAIP2 PABP-interacting protein 2 2.63E-14 -10.06 AF151052.1 Hs.396644

39 224782_at FLJ31121 hypothetical protein FLJ31121 1.50E-14 -10.05 AA205643 Hs.350194

40 242638_at ESTs 1.29E-14 -9.86 AA045088 Hs.62738

41 208652_at PPP2CA

protein phosphatase 2 (formerly 2A),

catalytic subunit, alpha isoform 6.38E-14 -9.86 BC000400.1 Hs.91773 42 225635_s_at

Homo sapiens cDNA FLJ13634 fis, clone

PLACE1011133. 1.63E-16 -9.84 AK023696.1 Hs.433024

43 209523_at TAF2

TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor,

150kDa 4.64E-13 9.80 AK001618.1 Hs.122752

44 203767_s_at STS

steroid sulfatase (microsomal),

arylsulfatase C, isozyme S 7.87E-17 -9.76 AU138166 Hs.79876

45 211495_x_at TNFSF13

tumor necrosis factor (ligand)

superfamily, member 13 1.32E-15 -9.74 AF114011.1 Hs.54673

46 200027_at - HG-U133A NARS asparaginyl-tRNA synthetase 4.51E-13 9.72 NM_004539.2 Hs.427212

47 244740_at

Homo sapiens, clone MGC:9913

IMAGE:3870821, mRNA, complete cds 1.10E-12 9.67 BE855713 Hs.23133

48 235523_at ESTs 4.11E-17 -9.66 AI275422 Hs.445845

49 231294_at ESTs 5.58E-13 9.65 AW445012 Hs.160918

(28)

51 212058_at SR140 U2-associated SR140 protein 9.33E-13 9.60 AB002330.1 Hs.7976

52 205761_s_at PP35

protein similar to E.coli yhdg and R.

capsulatus nifR3 4.38E-13 9.59 AW242981 Hs.97627

53 224068_x_at FLJ10290 hypothetical protein FLJ10290 2.30E-13 -9.58 U39402.1 Hs.25516

54 242715_at ESTs 7.52E-13 9.55 AA331548 Hs.240905

55 238892_at ESTs 3.25E-13 -9.54 AA703159 Hs.41840

56 220639_at FLJ22800 hypothetical protein FLJ22800 4.49E-14 -9.53 NM_024795.1 Hs.156652

57 210401_at P2RX1

purinergic receptor P2X, ligand-gated ion

channel, 1 2.11E-13 -9.51 U45448.1 Hs.41735

58 216008_s_at ARIH2 ariadne homolog 2 (Drosophila) 1.78E-12 9.39 AV694434 Hs.241558

59 211742_s_at EVI2B ecotropic viral integration site 2B 3.94E-13 -9.36 BC005926.1 Hs.5509

60 208826_x_at HINT1

histidine triad nucleotide binding protein

1 1.08E-12 -9.30 U27143.1 Hs.256697

61 214039_s_at LAPTM4B

lysosomal associated protein

transmembrane 4 beta 3.62E-12 9.30 T15777 Hs.296398

62 212160_at XPOT

exportin, tRNA (nuclear export receptor

for tRNAs) 3.71E-12 9.29 AI984005 Hs.380785

63 204249_s_at LMO2 LIM domain only 2 (rhombotin-like 1) 2.15E-12 9.29 NM_005574.2 Hs.184585

64 222902_s_at FLJ21144 hypothetical protein FLJ21144 2.69E-12 9.27 AU144258 Hs.59584

65 208772_at FLJ20288 FLJ20288 protein 4.46E-13 -9.25 AU160676 Hs.84045

66 204561_x_at APOC2 apolipoprotein C-II 1.17E-16 -9.25 NM_000483.2 Hs.75615

67 208628_s_at NSEP1

nuclease sensitive element binding

protein 1 3.30E-12 9.24 BC002411.1 Hs.74497

68 209995_s_at TCL1A T-cell leukemia/lymphoma 1A 1.43E-16 -9.22 BC003574.1 Hs.2484

69 209190_s_at DIAPH1 diaphanous homolog 1 (Drosophila) 6.43E-13 -9.21 AF051782.1 Hs.432623

70 218518_at C5orf5 chromosome 5 open reading frame 5 6.43E-13 -9.18 NM_016603.1 Hs.82035

71 226665_at DKFZp564C236 hypothetical protein DKFZp564C236 1.32E-14 -9.18 AI986239 Hs.378856

72 231897_at LTB4DH

leukotriene B4

12-hydroxydehydrogenase 6.35E-12 9.17 AL135787 Hs.114670

73 220360_at FLJ23320 hypothetical protein FLJ23320 1.12E-13 -9.17 NM_024672.1 Hs.85910

74 200066_at - HG-U133B IK IK cytokine, down-regulator of HLA II 2.69E-12 -9.16 AF182645.1 Hs.8024

75 229638_at IRX3 iroquois homeobox protein 3 4.15E-16 -9.14 AI681917 Hs.3321

76 227802_at

ESTs, Weakly similar to T34137 hypothetical protein C33G8.2 -

Caenorhabditis elegans [C.elegans] 2.44E-14 -9.14 AI075999 Hs.58290

77 207721_x_at HINT1

histidine triad nucleotide binding protein

1 2.15E-12 -9.12 NM_005340.1 Hs.256697

(29)

79 210292_s_at PCDH11X protocadherin 11 X-linked 3.71E-12 9.09 AF332218.1 Hs.374280

80 235422_at LOC51321 hypothetical protein LOC51321 1.73E-14 -9.08 AA977218 Hs.268122

81 217975_at LOC51186 pp21 homolog 7.42E-12 9.06 NM_016303.1 Hs.15984

82 241827_at

Homo sapiens cDNA FLJ39372 fis, clone PEBLM2007832, moderately similar to

ZINC FINGER PROTEIN 84. 7.45E-12 9.05 AL577866 Hs.262036

83 229814_at ESTs 4.43E-13 -9.04 BG149337 Hs.406106

84 39318_at TCL1A T-cell leukemia/lymphoma 1A 5.50E-16 -9.04 X82240 Hs.2484

85 238228_at

Homo sapiens cDNA FLJ25155 fis, clone

CBR07976. 1.10E-12 -9.02 AI732206 Hs.105414

86 208766_s_at HNRPR

heterogeneous nuclear ribonucleoprotein

R 6.35E-12 9.01 BC001449.1 Hs.15265

87 203166_at CFDP1 craniofacial development protein 1 2.34E-13 -9.00 NM_006324.1 Hs.433402

88 204082_at PBX3 pre-B-cell leukemia transcription factor 3 4.53E-13 -8.97 NM_006195.1 Hs.294101

89 239740_at ESTs 1.02E-11 8.97 BF436898 Hs.213352

90 232247_at FLJ14855 hypothetical protein FLJ14855 1.57E-11 8.91 BF969097 Hs.224843

91 225541_at

Homo sapiens mRNA; cDNA DKFZp586O1224 (from clone

DKFZp586O1224) 4.61E-12 -8.89 BE274422 Hs.380933

92 209499_x_at TNFSF13

tumor necrosis factor (ligand)

superfamily, member 13 3.74E-13 -8.88 BF448647 Hs.54673

93 212886_at DKFZP434C171 DKFZP434C171 protein 1.90E-13 -8.87 AL080169.1 Hs.209100

94 200093_s_at - HG-U133B HINT1

histidine triad nucleotide binding protein

1 9.58E-12 -8.86 N32864 Hs.256697

95 205611_at TNFSF12

tumor necrosis factor (ligand)

superfamily, member 12 2.44E-14 -8.86 NM_003809.1 Hs.26401

96 211671_s_at NR3C1

nuclear receptor subfamily 3, group C,

member 1 (glucocorticoid receptor) 6.82E-13 -8.86 U01351.1 Hs.75772

97 214500_at H2AFY H2A histone family, member Y 3.14E-13 -8.85 AF044286.1 Hs.75258

98 237265_at MGC35212 hypothetical protein MGC35212 1.43E-11 8.85 BF062257 Hs.127567

99 210009_s_at GOSR2 golgi SNAP receptor complex member 2 2.14E-12 -8.84 AF229796.1 Hs.100651

(30)

list_7 Pro-B-ALL/t(11q23) versus rest

Number Probe Set ID Gene Symbol Title q-value t-test statistic

Sequence

Derived From Unigene_Accession

1 224918_x_at MGST1 microsomal glutathione S-transferase 1 3.68E-185 -37.66 AI220117 Hs.389700

2 202722_s_at GFPT1

glutamine-fructose-6-phosphate

transaminase 1 8.39E-58 -37.33 NM_002056.1 Hs.1674

3 204949_at ICAM3 intercellular adhesion molecule 3 2.41E-97 -37.30 NM_002162.2 Hs.99995

4 217800_s_at NDFIP1 Nedd4 family interacting protein 1 1.12E-71 -36.06 NM_030571.1 Hs.9788

5 231736_x_at MGST1 microsomal glutathione S-transferase 1 1.26E-171 -35.55 NM_020300.1 Hs.389700

6 206011_at CASP1

caspase 1, apoptosis-related cysteine

protease (interleukin 1, beta, convertase) 6.85E-131 -35.16 AI719655 Hs.2490

7 244404_at ESTs 7.62E-60 -34.79 AI376134 Hs.35199

8 225782_at LOC253827 hypothetical protein LOC253827 1.18E-165 -34.78 BG171064 Hs.339024

9 217967_s_at C1orf24 chromosome 1 open reading frame 24 2.13E-93 -32.01 AF288391.1 Hs.48778

10 218942_at FLJ22055 hypothetical protein FLJ22055 1.42E-41 -31.67 NM_024779.1 Hs.144502

11 225790_at LOC253827 hypothetical protein LOC253827 9.28E-130 -29.34 BG171064 Hs.339024

12 204563_at SELL

selectin L (lymphocyte adhesion

molecule 1) 5.35E-63 -29.08 NM_000655.2 Hs.82848

13 203949_at MPO myeloperoxidase 1.25E-75 -28.86 NM_000250.1 Hs.1817

14 204214_s_at RAB32 RAB32, member RAS oncogene family 4.11E-41 -28.62 NM_006834.1 Hs.32217

15 217963_s_at NGFRAP1

nerve growth factor receptor

(TNFRSF16) associated protein 1 2.05E-121 -28.61 NM_014380.1 Hs.381039

16 219013_at GALNT11

UDP-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11

(GalNAc-T11) 1.31E-39 -28.39 NM_022087.1 Hs.97056

17 203948_s_at MPO myeloperoxidase 1.83E-116 -28.20 J02694.1 Hs.1817

18 241742_at PRAM-1 PRAM-1 protein 3.14E-96 -27.93 AW027174 Hs.239276

19 204487_s_at KCNQ1

potassium voltage-gated channel,

KQT-like subfamily, member 1 2.22E-90 -27.89 NM_000218.1 Hs.156115

20 227353_at EVER2 epidermodysplasia verruciformis 2 1.71E-32 -27.66 BE671663 Hs.15284

21 225637_at FLJ20186 hypothetical protein FLJ20186 4.69E-71 -27.60 BE676248 Hs.62771

(31)

23 203591_s_at CSF3R

colony stimulating factor 3 receptor

(granulocyte) 8.68E-91 -27.01 NM_000760.1 Hs.2175

24 206120_at CD33 CD33 antigen (gp67) 2.98E-101 -26.83 NM_001772.1 Hs.83731

25 227193_at

Homo sapiens, clone IMAGE:4828750,

mRNA 1.55E-102 -26.74 AI955713 Hs.375762

26 214172_x_at RYK RYK receptor-like tyrosine kinase 6.88E-28 -26.74 BG032035 Hs.79350

27 226352_at

Homo sapiens cDNA FLJ35156 fis, clone

PLACE6011057. 2.93E-80 -26.25 BF447037 Hs.294110

28 200995_at IPO7 importin 7 1.88E-31 -26.24 AL137335.1 Hs.5151

29 224094_at

Homo sapiens PRO1716 mRNA,

complete cds 3.63E-95 -26.15 AF118072.1 Hs.383401

30 220307_at CD244 natural killer cell receptor 2B4 2.20E-57 -26.11 NM_016382.1 Hs.157872

31 227769_at GPR27 G protein-coupled receptor 27 1.17E-78 -25.98 AI703476 Hs.356084

32 239771_at TIP120A TBP-interacting protein 4.77E-108 -25.89 BG399629 Hs.184786

33 205639_at AOAH acyloxyacyl hydrolase (neutrophil) 1.78E-74 -25.77 NM_001637.1 Hs.82542

34 210024_s_at UBE2E3

ubiquitin-conjugating enzyme E2E 3

(UBC4/5 homolog, yeast) 6.01E-26 -25.26 AB017644.1 Hs.4890

35 219229_at SLC21A11

solute carrier family 21 (organic anion

transporter), member 11 1.66E-35 -25.26 NM_013272.2 Hs.14805

36 202946_s_at BTBD3 BTB (POZ) domain containing 3 4.21E-70 -25.16 NM_014962.1 Hs.7935

37 210425_x_at GOLGIN-67 golgin-67 5.73E-80 -24.95 AF164622.1 Hs.182982

38 222764_at ASRGL1 asparaginase like 1 1.28E-46 -24.76 AI928342 Hs.7331

39 204446_s_at ALOX5 arachidonate 5-lipoxygenase 2.45E-67 -24.76 NM_000698.1 Hs.89499

40 214181_x_at LST1 leukocyte specific transcript 1 1.33E-51 -24.61 AI735692 Hs.380427

41 203471_s_at PLEK pleckstrin 2.49E-38 -24.40 NM_002664.1 Hs.77436

42 227266_s_at

Homo sapiens, clone IMAGE:4692106,

mRNA 5.87E-57 -24.36 BF679849 Hs.34192

43 232557_at

Homo sapiens mRNA; cDNA DKFZp547K056 (from clone

DKFZp547K056) 3.63E-57 -24.33 AU158526 Hs.296743

44 208146_s_at CPVL carboxypeptidase, vitellogenic-like 1.50E-85 -24.21 NM_031311.1 Hs.95594

45 214575_s_at AZU1

azurocidin 1 (cationic antimicrobial

protein 37) 7.21E-89 -24.21 NM_001700.1 Hs.72885

46 215633_x_at LST1 leukocyte specific transcript 1 2.08E-57 -24.10 AV713720 Hs.380427

47 228754_at KIAA1719 KIAA1719 protein 6.75E-32 -24.08 BG150485 Hs.296770

48 205051_s_at KIT

v-kit Hardy-Zuckerman 4 feline sarcoma

viral oncogene homolog 8.91E-95 -24.03 NM_000222.1 Hs.81665

(32)

50 214953_s_at APP

amyloid beta (A4) precursor protein

(protease nexin-II, Alzheimer disease) 1.89E-75 -23.91 X06989.1 Hs.177486

51 214574_x_at LST1 leukocyte specific transcript 1 1.39E-42 -23.72 NM_007161.1 Hs.380427

52 225386_s_at LOC92906 hypothetical protein BC008217 1.01E-66 -23.70 AI559701 Hs.91684

53 219615_s_at KCNK5

potassium channel, subfamily K, member

5 2.33E-45 -23.57 NM_003740.1 Hs.127007

54 228559_at

Homo sapiens, clone IMAGE:6043059,

mRNA 1.73E-66 -23.56 BF111626 Hs.55028

55 204122_at TYROBP

TYRO protein tyrosine kinase binding

protein 3.63E-57 -23.56 NM_003332.1 Hs.9963

56 216268_s_at JAG1 jagged 1 (Alagille syndrome) 7.00E-85 -23.56 U77914.1 Hs.91143

57 219694_at FLJ11127 hypothetical protein FLJ11127 8.55E-70 -23.49 NM_019018.1 Hs.91165

58 209099_x_at JAG1 jagged 1 (Alagille syndrome) 2.22E-80 -23.48 U73936.1 Hs.91143

59 204852_s_at PTPN7

protein tyrosine phosphatase,

non-receptor type 7 1.93E-24 -23.30 NM_002832.1 Hs.35

60 226764_at LOC152485 hypothetical protein LOC152485 2.61E-80 -23.24 BG542955 Hs.351270

61 237568_at ESTs 1.50E-85 -23.08 H67156 Hs.191196

62 205159_at CSF2RB

colony stimulating factor 2 receptor, beta,

low-affinity (granulocyte-macrophage) 6.67E-63 -23.05 AV756141 Hs.285401

63 203973_s_at CEBPD

CCAAT/enhancer binding protein

(C/EBP), delta 5.42E-38 -22.99 NM_005195.1 Hs.76722

64 237460_x_at ESTs 1.89E-72 -22.98 AV700174 Hs.296320

65 208438_s_at FGR

Gardner-Rasheed feline sarcoma viral

(v-fgr) oncogene homolog 8.51E-62 -22.89 NM_005248.1 Hs.1422

66 222422_s_at NDFIP1 Nedd4 family interacting protein 1 3.76E-27 -22.88 NM_030571.1 Hs.9788

67 202214_s_at CUL4B cullin 4B 5.10E-57 -22.74 NM_003588.1 Hs.155976

68 48117_at LOC112869 hypothetical protein BC011981 1.03E-29 -22.66 AA160496 Hs.110407

69 221235_s_at

Homo sapiens, clone IMAGE:3448872,

mRNA, partial cds 2.65E-33 -22.55 NM_030825.1 Hs.446350

70 204647_at HOMER3 homer homolog 3 (Drosophila) 1.12E-80 -22.55 NM_004838.1 Hs.424053

71 211429_s_at SERPINA1

serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase,

antitrypsin), member 1 7.91E-73 -22.46 AF119873.1 Hs.297681

72 217764_s_at RAB31 RAB31, member RAS oncogene family 5.21E-56 -22.44 AF183421.1 Hs.223025

73 223168_at ARHU ras homolog gene family, member U 2.44E-63 -22.31 AL096776 Hs.20252

(33)

75 204661_at CDW52 CDW52 antigen (CAMPATH-1 antigen) 8.78E-57 -22.23 NM_001803.1 Hs.276770 76 214875_x_at APLP2 amyloid beta (A4) precursor-like protein 2 1.83E-41 -22.20 AW001847 Hs.279518

77 226794_at STXBP5 syntaxin binding protein 5 (tomosyn) 3.50E-36 -22.18 AI825998 Hs.184319

78 221060_s_at TLR4 toll-like receptor 4 5.71E-72 -22.17 NM_003266.1 Hs.159239

79 242672_at ESTs 1.30E-32 -22.14 AA743129 Hs.372247

80 243618_s_at LOC152485 hypothetical protein LOC152485 7.26E-68 -22.12 BF678830 Hs.351270

81 205180_s_at ADAM8

a disintegrin and metalloproteinase

domain 8 4.44E-39 -22.04 NM_001109.1 Hs.86947

82 208702_x_at APLP2 amyloid beta (A4) precursor-like protein 2 3.91E-33 -21.97 BC000373.1 Hs.279518

83 210512_s_at VEGF vascular endothelial growth factor 7.99E-62 -21.91 AF022375.1 Hs.73793

84 209949_at NCF2

neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease,

autosomal 2) 1.92E-54 -21.87 BC001606.1 Hs.949

85 211506_s_at 1.35E-49 -21.78 AF043337.1

86 203799_at BIMLEC C-type lectin BIMLEC precursor 3.88E-31 -21.62 NM_014880.1 Hs.2441

87 244740_at

Homo sapiens, clone MGC:9913

IMAGE:3870821, mRNA, complete cds 7.89E-73 -21.62 BE855713 Hs.23133

88 217849_s_at CDC42BPB

CDC42 binding protein kinase beta

(DMPK-like) 1.65E-75 -21.44 NM_006035.1 Hs.12908

89 205624_at CPA3 carboxypeptidase A3 (mast cell) 5.31E-80 -21.43 NM_001870.1 Hs.646

90 205453_at HOXB2 homeo box B2 5.78E-54 -21.42 NM_002145.1 Hs.2733

91 211178_s_at PSTPIP1

proline-serine-threonine phosphatase

interacting protein 1 6.33E-45 -21.39 AF038602.1 Hs.129758

92 223319_at GPHN gephyrin 5.44E-78 -21.34 AF272663.1 Hs.13405

93 215034_s_at TM4SF1 transmembrane 4 superfamily member 1 6.77E-67 -21.33 AI189753 Hs.351316

94 219191_s_at BIN2 bridging integrator 2 5.08E-32 -21.32 NM_016293.1 Hs.14770

95 219646_at FLJ20186 hypothetical protein FLJ20186 1.34E-28 -21.30 NM_017702.1 Hs.62771

96 223136_at AIG-1 androgen induced protein 5.10E-57 -21.29 AF151861.1 Hs.107528

97 209879_at SELPLG selectin P ligand 3.22E-35 -21.26 AI741056 Hs.79283

98 227647_at KCNE3

potassium voltage-gated channel,

Isk-related family, member 3 3.57E-45 -21.23 AI692703 Hs.30715

99 201984_s_at EGFR

epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b)

(34)

References

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