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Outcomes of Cognitive Behavioral Therapy

Interventions in Children and Adolescents Affected by

Armed Conflict- A Systematic Review

A paper presented to the faculty of The University of North Carolina at Chapel Hill in partial fulfillment of the requirements for the degree of Master of (Master of Science in) Public Health in the Department of Maternal and Child Health. Chapel Hill, N.C.

Katie Mitchell

3-31-2015

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Outcomes of Cognitive Behavioral Therapy Interventions in Children and Adolescents Affected by Armed Conflict- A Systematic Review

Abstract

Introduction: There are more than 1 billion children under the age of 18 living in countries affected by armed conflict. In children and adolescents, exposure to armed conflict has been associated with negative consequences on mental health and psychological wellbeing. Despite the apparent

international consensus on programmatic strategies for psychosocial support programs, there is still a significant amount of disagreement in regards to which interventions are most effective. This review compared outcomes of various cognitive behavioral therapy (CBT) studies in reducing the severity of PTSD symptoms in youth affected by conflict or war. Methods: The review complemented an earlier review of randomized control trials by restricting the search to non-randomized trails. An extensive effort to identify grey literature sources was undertaken, utilizing database searches and bibliography mining. Results: Out of 98 studies identified, seven were included in this review. CBT interventions reduced psychiatric symptoms in six of the seven (86%) studies. The seventh study found no change in PTSD or depression scores in the intervention group, but did note a non-significant decline in intrusion scores. Conclusion: This systematic review supports the findings of an earlier review of randomized control trials, with both demonstrating that CBT may successfully help children and adolescents affected by armed conflict in reducing PTSD symptoms. Yet there is still a significant amount of heterogeneity among interventions and measurement tools, making it challenging to truly compare the effectiveness of different CBT intervention. Therefore, future research should focus on establishing a consensus on measureable outcomes and the necessary key components for a successful program.

Introduction

There are more than 1 billion children under the age of 18 living in countries affected by

armed conflict (Machel, 2009). The impact of armed conflicts goes beyond the destruction of

physical property, to disrupting families and severing social networks, closing schools, and

rupturing social services (Betancourt et al. 2008, & Tol et al. 2013). For children and

adolescents, exposure to armed conflict has been associated with negative consequences on

mental health and psychological wellbeing (Tol et al. 2011, & Tol et al. 2013, & Betancourt et al.

2008). The affects can be transient such as distress or behavioral problems or more long-term

including anxiety and conduct disorders as well as major depression (Tol et al. 2011, & Tol et al.

2013). The most studied mental health disorders in conflict affected areas are post-traumatic

stress disorder (PTSD) and major depression. (Tol et al. 2011, & Tol et al. 2013) In a

(3)

analysis conducted by Attanayake et al. in 2009 reviewing 17 studies with 7,920 children

exposed to war, researchers found pooled prevalence rates of 47% for PTSD and 53% for major

depression (Attanayake et al., 2009).

With the growing knowledge of the impact of armed conflict on the mental health of

children and adolescents, increasingly humanitarian organizations are implementing

psychosocial support programs. In 2007, the Inter-Agency Standing Committee (IASC) even

established a set of objectives and programmatic strategies for psychosocial support in

emergency settings. Despite the apparent international consensus on programmatic strategies,

there is still a significant amount of disagreement surrounding which interventions are most

effective, the timing of said interventions, and the dominant focus on PTSD (Tol et al., 2011).

The differences in opinions are exacerbated by the limited number of rigorous evaluations of

interventions in low and middle income countries (LAMIC) affected by war.

Cognitive behavioral therapy (CBT) is one of the interventions that has been shown in

high income countries to be effective in treating PTSD and depression. In a review of

meta-analyses conducted by Butler and colleagues (2004), findings demonstrated that trauma

focused cognitive behavioral therapy (TF-CBT), for a wide range of incidents from accidents to

assaults, had significant benefits on all measured PTSD symptoms when compared to waitlist

control groups. Additionally, there was also evidence that TF-CBT had significant effects on

depression and anxiety. Evidence from the meta-analysis also suggests that cognitive therapy

has sustained effects after treatment has concluded, specifically for depression, anxiety, and

childhood internalizing disorders. Randomized trials from low-income and middle-income

(4)

countries, although limited, have resulted in similar findings (Rahman et al. 2008, & Rojas et al.

2007, & Patel et al. 2007).

In a recent systematic review conducted by the author, comparing the outcomes of

randomized control trials with children and adolescents affected by war; CBT was found to

reduce psychiatric symptoms in five of the eight (63%) studies reviewed. Two of the three

studies indicating no intervention effect on psychiatric symptoms, did find a reduction in

conduct problems, a decrease in aggression in boys and an increase in pro-social behavior in

girls. However, it was concluded that more evidence would be needed in order to recommend

CBT for the population of interest.

The objective of this systematic review is again to compare the outcomes of cognitive

behavioral therapy in war-affected youth, but focusing non-randomized trials and other grey

literature sources excluded from the previous review. Taking a more inclusionist view is

particularly important when considering interventions with war-affected individuals, as other

study designs beside randomized control trials may provide more insight into adaptive

challenges, as well as challenges that are population-based and involve multiple stakeholders

(Schorr, L., 2012). In addition, a large number of humanitarian organizations are implementing

mental health programs and their results as well as insights into implementation strategies are

less likely to appear in peer-reviewed journals. This review will complement the review of

randomized control trials and add to the growing knowledge on outcomes of CBT interventions

in youth affected by war or conflict.

(5)

Methods

Studies were identified through a systematic literature search between January and

February 2015 using fourteen databases including PubMed, EMBASE and PsycINFO1. The search

identified interventions evaluating the use of cognitive behavioral therapy to support children

and adolescents affected by conflict or war. For this particular review, randomized control trials

were not included. Returns were limited to studies that contained keywords within the title or

abstract. The following search terms were utilized: “PTSD and posttraumatic stress disorder”

and “youth or adolescent(s) or teen(s) or teenager(s), child or children” and “cognitive

behavioral therapy or CBT or cognitive therapy”. To further focus the search on war or

conflict-affected children and adolescents “war or conflict zone” were included to the search terms.

Given large gaps in peer-reviewed literature a google search was conducted using the

following search terms: cognitive behavioral therapy + war + child. In addition, the websites of

twelve organizations2 who work with children or adolescents affected by war or conflict were

searched using broad keywords (cbt, cognitive behavioral therapy and/ or mental health). The

decision to use broad keywords when searching organization websites was based on

recommendations provided by the Health and Life Sciences Library at the University of

Pennsylvania (guides.library.penn.edu). Organizations were identified by the author through

1 Databases searched: PubMed, EMBASE, PsycINFO, Africa-Wide Information, Anthropology Plus, CINAHL Plus with Full Text, Family & Society Studies Worldwide, Global Health, Health and Psychosocial Instruments, Middle Eastern & Central Asian Studies, PsycARTICLES, PsycCRITIQUES, Social Work Abstracts, Proquest

2 IRC, IMC, War Child Holland, CARE International, Catholic Relief Services, Gates, World Vision, Carter Foundation, War Trauma Foundation, UNHCR, UNICEF, USAID

(6)

google searches for institutions working with children affected by conflict or war, as well as

through previous knowledge from studying the field.

For a more extensive search, studies were identified through bibliography mining and

recommendations from an expert in the field. These additional two steps were conducted

primarily because initial searches contained a significant number of reviews. In order to find the

original intervention articles being reviewed, the author scanned the reference lists of several

comprehensive reviews on CBT. To find more recent articles the author contacted an expert in

the field who provided a list of additional journals that regularly publish information on the

topic area.

Articles subject to full review were those that adhered to the following criteria: (1) the

publication described a cognitive behavioral therapy intervention, (2) children or adolescents

were the primary recipients of the intervention, (3) the intervention was administered in a

conflict or war affected region or with newly resettled refugees. In addition, there were no

restrictions on sample size or duration of time since exposure to conflict. Studies were excluded

if they were not in English or were published before the year 2000. Articles were also excluded

if the study population were war veterans or children of veterans.

The following domains were extracted from relevant studies: study region, type of

study, sample size, description of study, adaptation of CBT program, measurement tools and

adaptation of measurement tools, study setting, follow-up period, service providers,

comparison groups and outcomes. In addition to extracted domains, notable limitations (either

noted by the author or identified during the review) were documented in the review process.

(7)

Results

Out of 98 articles initially identified from the 14 databases utilized, google searching and

bibliography mining, only 47 publications were studying the effectiveness of CBT methodologies

in youth directly affected by war. After removing duplicates, studies relating to veterans or

children of veterans, articles published before 2000, and studies not in English, 23 articles were

remaining. The final 16 articles were removed because they were reviews or guidelines, not

actual intervention studies. In total, seven of the initial 98 studies were included in the review.

Figure 1 presents the flow of information through the different phases of the review.

90 articles found through database searches using keywords related to PTSD, children, and CBT

74 articles when excluding RCTs

60 articles when limited to articles focusing on children/ youth from developing countries

45 articles when studies with veterans and children of veterans are excluded

38 articles when studies before 2000 were excluded and studies not in English

30 articles when duplicates and articles not available online were removed

47 articles when excluding articles not focusing on CBT

23 additional articles were removed because they were reviews/ guidelines/ not interventions

8 additional articles found through google searching and bibliography mining

7 studies included in the systematic

review (n= 231) Figure 1: Flow chart of systematic review

(8)

The studies were conducted in six different countries with two studies taking place in

Uganda. Of the seven studies, four were conducted with adolescent refugees, one with

adolescent survivors of the Rwandan genocide, two in post-conflict regions and one with

children in Gaza experiencing continued exposure to violence. Four of the seven studies were

group interventions focusing on secondary prevention strategies. One study provided a

combination of individual, group and family sessions (Mӧhlen et al., 2005) and the remaining

two studies were individual focused (Onyut et al., 2005 & Schauer et al., 2004). Of the seven

studies, four were specifically based in schools with children ranging in ages from 9-19 years.

The remaining three studies were conducted in refugee accommodations or a Ugandan refugee

camp project site (Mӧhlen et al., 2005 & Onyut et al., 2005 & Schauer et al., 2004). The length

of interventions was between four and 20 sessions and five of the trials specified follow-up

periods ranging from two to nine months. Further details of study characteristics can be found

in Table 1 and 2.

Although all interventions were considered a form of cognitive behavioral therapy;

studies used various techniques as well as different manualized programs including: Teaching

Recovery Techniques, trauma and grief-focused psychotherapy, KIDNET, a multimodal therapy

model, a rumination-focused cognitive and behavioral intervention, and Group Crisis

Intervention. Specific information on the individual components of CBT used in each study can

be found in Table 1.

Methodology Results

Six of the seven studies measured more than one outcome, the most common of which

were PTSD and depression. The seventh study by Schauer and colleagues (2004) only measured

(9)

PTSD symptoms. Sezibera and colleagues (2005) in addition to examining psychological

symptomology also measured somatization symptoms such as shortness of breath, nausea and

chest pains. Two studies collected additional information on the types and or frequency of

war-related traumas. Ehntholt et al. used the War Trauma Questionnaire (WTQ) which asks children

questions regarding events they may have experienced during war and Mӧhlen and colleagues

used the Harvard Trauma Questionnaire (HTQ) to determine the degree of traumatization.

(Table 1)

Outcomes of interest were monitored using different psychometric instruments. None

of the seven studies provided detailed descriptions of instrument adaptation processes. That

being said, three studies did mention instruments had been translated into local languages

(Layne et al., 2001 & Schauer et al., 2004 & Sezibera et al. 2009) and two studies noted that the

instruments had previously been adapted or validated for the study population (Ehntholt et al.,

2005 & Thabet et al., 2005). (Table 1)

Six of the seven studies had children self-report symptoms and outcomes. In addition to

a self-report assessment, Mӧhlen and colleagues (2005) also utilized semi-structured diagnostic

interviews conducted by a clinical psychologist. The studies using the child-friendly version of

narrative exposure therapy (KIDNET), utilized self-report questionnaires to provide quantitative

data on symptomology changes, but also provided qualitative data including verbatim

descriptions of war-related traumas as well as changes in moods and psychological well-being

post-intervention (Onyut et al., 2005 & Schauer et al., 2004).

Among the seven studies reviewed, only two mentioned cultural adaptation of the

intervention had occurred, but no further details were provided (Sezibera et al., 2009 & Thabet

(10)

et al., 2005). Layne and colleagues (2001) had a unique situation in which the intervention was

specifically designed for children in Bosnia-Herzegovina by the University of California. The

intervention had also previously been piloted in several schools across the country. (Table 1)

(11)

Table 1: Description of the Intervention and Psychometric Instruments

Study Country of Origin Type of study Participants Description CBT Components CBT Adaptation Measurement Tools Measurement Adaptation

Ehntholt

2005 England

Pilot Study- prospective experimental study 26 refugee children ages 11-15 from various countries Teaching recovery techniques: intervention lasted for 6 weeks, consisting of weekly 1-hour sessions Education about symptoms of PTSD, Coping Strategies, Dual attention techniques, Breathing/ Relaxation skills, Encouraged drawing and

writing None noted

Birleson Depression Self-Rating Scale (DSRS) SDQ War Trauma Questionnaire (WTQ) Revised Children's Manifest Anxiety Scale WTQ- adapted for use throughout Bosnia-Herzegovina by UNICEF, adapted further for study Layne

2001 Bosnia and Herzegovina

(12)

Table 1: Description of the Intervention and Psychometric Instruments

Study Country of Origin Type of study Participants Description CBT Components CBT Adaptation Measurement Tools Measurement Adaptation

Mӧhlen

2005 Germany

Prospective experimental study 10 Kosovian refugees ages 10-16 years Multimodal manual based intervention program, 12 weeks, 1 session with parents

Trauma- and grief focusing therapy; Verbalizing; Relaxation techniques; Painting, playing, acting, and guided imagery; Group discussions, and Psychoeducation about trauma and trauma reactions None noted (developed by authors) Structured diagnostic interviews, Harvard Trauma Questionnaire (HTQ), Diagnostic System for System Psychological Disorders, Children's Global Assessment

Scale None Noted

Onyut

2005 Uganda Pilot Study and Case reports

6 Somali refugees ages 13-17 KIDNET, 4-6 individual sessions Child-friendly version of Narrative Exposure Therapy, describe the events of the past, present and hopes/

aspirations for the future None noted (developed by authors) Posttraumatic Diagnostic Scale, Hopkins Symptom Checklist- 25, Composite international diagnostic interview

(CIDI)- K and E None Noted

(13)

Table 1: Description of the Intervention and Psychometric Instruments

Study Country of Origin Type of study Participants Description CBT Components CBT Adaptation Measurement Tools Measurement Adaptation

Schauer

2004 Uganda Case Study

1 Somali refugee, 13 years old

KIDNET, 4 individual sessions over 3 weeks Child-friendly version of Narrative Exposure Therapy, describe the events of the past, present and hopes/

aspirations for the future, and

psychoeducation None noted

Post-traumatic Stress

Diagnostic

Scale Translated

Sezibera

2009 Rwanda

Prospective experimental study 22 survivors of 1994 genocide aged 15-18 years Rumination-focused cognitive and behavioral intervention, 10 weekly sessions for 2 hours Pychoeducation, narrative exposure, ID cognitions, emotions and behaviors associated with trauma of genocide, Coping strategies, Rumination, Monitoring anxiety and depression signals

Based on the protocols of Borkovec and Watkins- No further description of adaptation for population UCLA-PTSD Index Brief Symptom Inventory, Assessment

questionnaires Translated

(14)

Table 1: Description of the Intervention and Psychometric Instruments

Study Country of Origin Type of study Participants Description CBT Components CBT Adaptation Measurement Tools Measurement Adaptation

Thabet

2005 Gaza

Prospective experimental study 111 children from 5 refugee camps in Gaza Strip aged 9-15 years Group Crisis Intervention, 7 weekly sessions Free drawing, Talking about traumatic experiences and feelings, Writing about traumatic events, Storytelling, Games, and Role-play related to the conflict

(15)

Outcome Results

Six of the seven studies indicated a decline in PTSD symptoms post-intervention. The

seventh study by Thabet and colleagues (2005) saw no change in PTSD or depression scores in

the intervention group, but did note a non-significant decrease in intrusion scores: z (47)=1.87,

p =0.06. Three studies specifically noted that PTSD scores had remitted to a degree below the

diagnostic threshold for PTSD, either immediately post-intervention or upon follow-up (Onyut

et al., 2005 & Schauer et al., 2004 & Sezibera et al., 2009). Outcomes for other measures such

as depression and anxiety varied across studies. (Table 2)

In the two studies from Uganda using KIDNET, both indicated significant reductions in

PTSD symptoms (Onyut et al., 2005 & Schauer et al., 2004). Onyut and colleagues (2005) also

noted significant declines in depression to non-clinical levels in four individuals who presented

with depression at pre-test. The effects of the intervention in both studies, either was

maintained or improved after the six or nine month follow-up periods. (Table 2)

Two of the studies were conducted with adolescent refugees who had recently resettled

in England or Germany (Mӧhlen et al., 2005 & Enhtholt et al., 2005). Both interventions

resulted in significant decreases in PTSD symptoms. Mӧhlen and colleagues (2005) also noted a

significant decline in the severity of depression symptoms (Wilcoxon, p = 0.014), which was not

found in the Ehntholt et al. study. Additionally, Mӧhlen and colleagues also measured

psychosocial functioning and found a substantial increase in functioning for nine of the ten

students in the study. (Table 2)

Sezibera and colleagues (2009) and Thabet and colleagues (2005) were the only ones in

their analysis to look at the effect or interaction of gender or age on the intervention outcome,

(16)

but found the decline in PTSD occurred irrespective of either covariate. In addition, Sezibera et

al. was the only study that measured the impact of a cognitive behavioral intervention on

somatization, but found no significant impact on somatization symptomology in the study

population: F(1, 21) = 2.97, p> 0.05. (Table 2)

Finally, only one study specifically noted that their intervention was provided in

conjunction with another program. The Layne and colleagues (2001) study was conducted in

conjunction with a larger UNICEF initiative in the country, promoting post-war adaptation in

youth affected by war.

(17)

Table 2: Intervention Outcomes and Limitations

Study Study Setting Follow-up CBT Service Providers Comparison Group Outcome Limitations

Ehntholt 2005

Secondary schools in

London 2 months

Clinical psychology trainee Wait-list Control Group

Significant decrease in overall PTSD symptoms within the CBT group (t(14) = 2.934, p=.011)

CBT group showed a significant reduction in intrusive symptoms (t(14) = 3.826, p = .002)

No significant difference between groups on the total depression score Non-significant trend towards a decrease in anxiety in the CBT group over time (t(14) = 1.581, p = .136)

Limited follow-up time Small sample size No SDQ at follow-up

No established cut-off scores for self-report questionnaires for refugee population

Self-report assessment and measurement

Teachers not blinded to treatment group Children from different

countries, experienced different exposures

Layne

2001 Secondary schools in Bosnia None

Trained school

counselors Within-study

Participation in group psychotherapy was associated with significant reductions in PTSD, depression and grief compared to pre-treatment. No significant difference between students who completed all the modules or only some

Complications with supervision and training of counselors Less than half the schools competed the modules No control group No follow-up Predominately boys

No breakdown of locations of schools in Bosnia

Mӧhlen

2005 Refugee accommodations None

Trained medical

student Within-study

PTSD symptom severity score declined significantly ( t -test, p = 0.018), as well as the symptom scores of depression (Wilcoxon, p = 0.014) and anxiety (Wilcoxon, p = 0.006) CGAS score- 9 of 10 subjects showed an increase of at least 10 points indicating a substantial gain in psychosocial functioning

No follow-up

No adaptation of instruments Limited sample size

No quotes in discussion to support impact on children

(18)

Table 2: Intervention Outcomes and Limitations

Study Study Setting Follow-up CBT Service Providers Comparison Group Outcome Limitations

Onyut

2005 Not specified 9 months

Expert clinicians experienced

in NET Within-study

Decline in overall mean PTSD scores for all participants (pre-test mean score 14.3, post-test 9, follow-up 6.2) After 9 months, 4 of 6 participants no longer met criteria for PTSD

Significant depression remitted to non-clinical levels in 4 individuals who presented with depression at pretest

No adaptation of instruments No established cut-off scores for refugee population

Schauer 2004

Project base in Nakivale Camp, last session in an office in Mbarara

town 6 months

Experienced female NET therapist, a female NET trainee and a male refugee Somali NET trainee, who acted as

interpreter Within-study

Post-test revealed that the

participants symptoms had remitted to a degree below the diagnostic threshold for PTSD (36 to 12) Avoidance symptoms had gone down to zero and intrusive symptoms had also disappeared almost completely Hyperarousal no longer interfered with life

No adaptation of instruments No established cut-off scores for refugee population

Sezibera

2009 School setting 2 months Not specified Within-study

18.2% of participants no longer met PTSD diagnostic criteria at post-test Maintained at follow-up (17%) No gender differences Did not significantly impact depression or somatization

Small sample size

No adaptation of instruments or intervention

No established cut-off scores for refugee population

Short timeframe for follow-up

(19)

Table 2: Intervention Outcomes and Limitations

Study Study Setting Follow-up CBT Service Providers Comparison Group Outcome Limitations

Thabet

2005 School setting 3 months

4 clinicians as well as teachers

Wait-list Control Group and education only group

No significant changes were found, with the exception of the decrease in intrusion scores in the intervention group: z (47)=1.87,p =0.06, although this did not reach a level of statistical significance

There was no significant change from clinical to non-clinical PTSD range within any of the groups

Self-report instruments No detail about cultural adaptation of instruments or intervention

Only females in education group Did not measure current exposure levels of violence

(20)

Discussion

This paper summarizes the outcomes from seven studies using a form of cognitive

behavioral therapy with 231 children affected by war or conflict. The studies were

predominately from LAMIC with the exception of two studies from Western Europe with newly

resettled refugees. Participants included Somali refugees, children exposed to shellings in Gaza,

children impacted by war in Bosnia and Kosovo and adolescent survivors of the Rwandan

genocide. The interventions used various forms of cognitive behavioral therapy including:

Teaching Recovery Techniques, trauma and grief-focused psychotherapy, KIDNET, a multimodal

therapy model, a rumination-focused cognitive and behavioral intervention, and Group Crisis

Intervention. There was a significant amount of heterogeneity in the psychometric instruments

utilized, duration since exposure to conflict, provider qualifications, intervention settings and

follow-up periods. This observation is consistent with previous systematic reviews noting the

diversity in interventions and outcomes (Tol et al., 2011, & Tol et al., 2013).

Six of the seven studies (86%) found an intervention effect on psychiatric symptoms.

The seventh study by Thabet and colleagues (2005) saw no change in PTSD or depression scores

in the intervention group, but did note a non-significant decline in intrusion scores. Three

studies (43%) found that PTSD scores had remitted to a degree below the diagnostic threshold

for PTSD, either immediately post-intervention or upon follow-up (Onyut et al., 2005 & Schauer

et al., 2004 & Sezibera et al., 2009). These results are similar to findings from randomized

control trials not included in this review, such as a school-based resilience program

(ERASE-Stress) implemented in Israel. Researchers found a significant decrease in PTSD, functional

impairments and depression among war-affected children (Gelkopf & Berger, 2009). In an

(21)

evaluation of a CBT-based intervention (EMPOWER program) for war-affected internally

displaced persons in northern Uganda, researchers found reductions in depression and anxiety

like syndromes as well as a significant increase in pro-social behaviors in the intervention group

(Sonderegger et al., 2011). Finally, an intervention with Bosnian mothers found that there were

small improvements in the mother’s mental health as well as children’s psychological

functioning (Dybdahl, R., 2001).

In regards to sustained effects of interventions, as mentioned earlier, three studies, the

two KIDNET studies from Uganda and the Sezibera et al. study from Rwanda, had sustained

effects. These finding are congruent with other studies conducted in high incomes countries

(Butler et al., 2004, & Bryant et al., 2003). Conversely, Ehntholt and colleagues (2005) found no

significant treatment effects after two months. The authors suggest that findings may have

been influenced by a resurgence of violence in Macedonia during the two month follow-up

period. Many of the Kosovan refugees participating in the intervention had family and friends

living in Macedonia and it was hypothesized that the new images of violence may have stirred

up old memories of past war traumas. To help maintain the initial improvements, Ehntholt and

colleagues (2005) suggest future interventions provide “booster” sessions as well as include

sessions for parents and families.

Two studies examined the effect of gender in their analysis, and found no association

between gender and the intervention outcome (Sezibera et al., 2009 & Thabet et al., 2005). The

absence of gender effects is inconsistent with previous psychosocial interventions in children

and adolescents affected by conflict (Tol et al., 2008, & Bolton et al., 2007, & Wolmer et al.,

2011). In two randomized control trials conducted in Gaza and Israel, researchers found greater

(22)

intervention benefits for boys (Quota et al., 2012, & Berger et al., 2007). In addition, in a study

conducted by Bolton and colleagues (2007) in Northern Uganda, researchers reported

intervention effects only among girls. Ehntholt and colleagues (2005) did not conduct any

statistical analysis of gender differences but did make two important observations. The authors

found that mixed-gender groups were effective in increasing participation in boys, because

hearing the girls, who were more likely to share their experiences, encouraged the boys to do

so as well. A challenge noted by Ehntholt et al., was engaging 15-16 year old Kosovan Albanian

boys, who saw participation in discussions about emotions as well as the past as a sign of

weakness. Although not statistically supported, these two important observations may help

inform future program design or community engagement strategies.

In addition to observations regarding gender differences, Ehntholt and colleagues (2005)

share other key implementation challenges faced while instituting the Teaching Recovery

Techniques program in London schools. Researchers found that several of the secondary

schools were significantly understaffed and sometimes violent settings. Also due to the large

size of one of the schools, teachers found filling out the Strengths and Difficulties Questionnaire

(SDQ) challenging as they did not know students well enough. Ehntholt and colleagues explain

that although these schools do not seem like ideal settings for therapeutic groups, these inner

city London schools are often the ones new resettled refugees will attend. The authors

emphasize that as this type of school-based intervention can be incredibly difficult and

time-consuming it is essential to have a dedicated staff member, whom refugee children trust, to

implement this program.

(23)

Layne and colleagues (2001), similar to the Ehntholt study, describe the importance of

understanding and considering the social, economic and political context in which one plans to

implement a program. The authors encourage individuals to not only ask, does the intervention

work and how, but is the program right for the population at this time and with the resources

available. A perfect example is the Thabet et al. study, which was the only study in this review

where conflict was ongoing. It was also the only study that reported no significant intervention

effect on PTSD symptoms. The authors hypothesize that the continuous exposure to direct and

indirect trauma led to a sustained state of distress in the children, diminishing the intervention

effects. It may be possible, that at this time, a cognitive behavioral intervention may not be

appropriate for this population. Thabet and colleagues (2005) suggest that intervention

adaptations should occur for locations experiencing ongoing violence.

Although the above studies did discuss the importance of understanding cultural

context none of the studies reviewed provided detailed information on cultural adaptation

processes of the psychometric tools or interventions.

Limitations

The results of this review should be interpreted in light of several limitations. The

inclusion of PTSD in the search terms without including other mental health disorders may have

led to an unintentional exclusion of certain studies. Data extraction from the articles was only

completed by one reviewer, who may have had biases in selection and documentation. In

addition, as the reviewer only spoke English, all other non-English-language studies were

excluded. Original validation papers were not reviewed to assess quality of validation and

finally, the original authors were not contacted for clarification.

(24)

Implications

More rigorous studies on CBT are necessary but also more homogenous studies.

Researchers use a wide variety of psychometric measurements as well as cultural adaptation

and validation processes. In addition, there is little consensus on the number of sessions, length

of the intervention, intervention setting, provider qualifications as well as follow-up period.

Studies also do not always measure the extent of traumatic events experienced by children

which has been shown by previous studies to be associated with the level of psychological

distress (Mӧhlen et al., 2005). The significant heterogeneity in intervention designs creates a

challenge when trying to make comparisons between studies. Furthermore, certain

components of CBT may be more effective than others, and the heterogeneity of CBT

techniques utilized may be contributing to the variable findings.

Conclusion

This systematic review supports the findings of an earlier review of randomized control

trials, with both demonstrating that CBT may successfully help children and adolescents

affected by armed conflict in reducing PTSD symptoms. In addition, the two reviews also

demonstrate that CBT can be effective in a variety of contexts and among diverse populations.

Yet there is still a significant amount of heterogeneity among interventions and measurement

tools, making it challenging to truly compare the effectiveness of different CBT programs. As a

result, it is clear that one key direction for future research is to identify the core components of

a successful intervention. As stated by Lisbeth Schorr in her 2012 Boarder Evidence for Bigger

Impact article, "Focusing on spreading the identified components of effective interventions is

often more promising than attempting to replicate entire programs, because even proven

(25)

models are seldom so strong that the program will be successful regardless of the

circumstances in which it is replicated." The articles presented in this review are a perfect

example of the various types of conflicts, intervention settings, as well as degrees of trauma

affecting children and adolescents impacted by war. Analyzing successful CBT interventions can

help researchers and providers identify common factors or techniques, which can later be

applied to improve existing CBT programs or to design new interventions. In addition to

examining programmatic components, it is also important to extract critical implementation

strategies, such as level of training of mental health providers. Finally, understanding

contextual conditions is also key, such as the health infrastructure, regulations or funding

sources (Schorr, L., 2012).

Another direction for future research is the identification and subsequent consensus on

measurable outcomes for children and adolescents sought by CBT interventions. As seen in the

current review, studies not only vary in design but also in the expected outcomes, which only

increases the heterogeneity in measurement tools and intervention components. The use of

CBT in reducing PTSD in children and adolescents affected by war and conflict shows promise,

and by establishing a consensus on measureable outcomes and the necessary key components

for a successful program, providers can continue to enhance the effectiveness of CBT

interventions for youth affected by war.

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References

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Figure

Figure 1 presents the flow of information through the different phases of the review.
Table 1: Description of the Intervention and Psychometric Instruments
Table 1: Description of the Intervention and Psychometric Instruments
Table 1: Description of the Intervention and Psychometric Instruments
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References

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