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What can be learned from intermediate filament gene regulation in the mouse embryo

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Figure

Fig. 1. 5' regulatory elementsof classA. Benazzouz).presencedevelopmentalor severaldata from IIIIF genes.Schematicrepresentationof 5' regulatoryelementsof IF genes from class III:GFAP, peripherin,desminand vimentin.The namesof sequencescorresponding to kno
Fig. 2. Expressionofperoxydase-conjugatedpositivestaining. GFAP-Iac-Zin theembryoandin theadultmousebrain.Upstreamsequences(-1913 to +92) fromthe murineGFAP genewere linked to thelac-Zreportergeneandtheresultingconstructwas used to generatetransgenicmice
Fig. 3. Initial expressionoftransgene peripherin-Iac-Zin 13-dayp.c.embryos.Therransgenecontains5.8kbof peripherinupstreamsequenceslinked to the lac-Z reportergene.(AJ Lateral.tS! dorsalview.Notetheprominentexpressionin ganglia
Fig. 4. Vimentin (A) and desmin(B) expressionin 9-daytransgenicembryos:lateralviews.Embryos were stained for beta-galactosidaseThevimentintransgenewas generatedby insertionofthelac-Zgene inside the endogenousgenefromembryonic stem cells in framewith the N-

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