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Influence of cell type and cell culture media on the propagation of foot and mouth disease virus with regard to vaccine quality

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Figure

Fig. 1 3D structure with mutations acquired during adaption of FMDV strains A24 Cruzeiro and O1 Manisa
Fig. 2 Sensitivity of O1 Manisa and A24 Cruzeiro and their derivatives to acidic pH Equal amounts of virus of the different passages and culture systemswere incubated in buffers of different pH for 30 min, then neutralized and titrated
Fig. 3 Virus infection kinetics on monolayer and suspension BHK cells. Virus infection kinetics were performed using the virus variants A24-2P toinfect the suspension BHK-2P cell line, maintained in BHK200 (red line) or GMEM + 5% FCS (blue line) and A24–17

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