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Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

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Academic year: 2020

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Figure

Fig. 1 Coreceptor and costimulation blockade facilitates survival and maturation of hESC-derived pancreatic islets in NOD.Foxp3hCD2 mice
Fig. 2 Coreceptor and costimulation blockade promotes transplant tolerance to hESC-derived tissues through CD4+ Treg
Fig. 3 Coreceptor and costimulation blockade-induced transplant tolerance is predominantly mediated by intragraft proliferation of CD4+ Treg
Table 2 Distribution of cell number and percentage of CD4+Treg during rejection and tolerance in each of the cell cyclephases as determined by Scran
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