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Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types

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Academic year: 2020

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Figure

Fig. 1 Monocyte-specific psoriasis sub-network. To create the sub-network, the protein products of all psoriasis-associated genes (squares) and theirinteracting partners (circles) were identified
Fig. 2 Overview of the GSC, text-mining and GSO methods. (A) For the GSC method, percentile-normalized relative gene expression scores areintegrated with PPI data to create interactomes
Fig. 3 Heat map of a subset of the disease–cell-type associations identified by the GSC method
Table 1 Number of disease–cell-type associations identified bythe GSC and GSO methods supported by text-mining at a 10 %FDR
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