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pTuneos: prioritizing tumor neoantigens from next-generation sequencing data

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Figure

Fig. 1 pTuneospresentation and T cell recognition probability of neopeptides based on five related features
Fig. 2 aRuntime efficiency comparison of Rank coverage score (RCS) of the final rank list obtained from pTuneos Pre&RecNeo, MuPeXI, and Neopepsee, tested on the MEL dataset
Fig. 3 aoverall tumor neoantigen immunogenicity score (TNS), cytolytic activity, MSI status, and MHC II expression
Fig. 4 a High MHC-II expression score (> median) is more significantly correlated with low overall neoantigen immunogenicity score (p = 0.0007)than mutation burden and neoantigen burden, while cytolytic activity did not correlate with mutation burden, neoa
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